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Bis(triphenylphosphine)palladium(II) diacetate

CAS 14588-08-0[(C6H5)3P]2Pd(CH3COO)2Catalysis & Inorganic

Bis(triphenylphosphine)palladium(II) diacetate (CAS: 14588-08-0) is a palladium-based organometallic compound with the formula [(C6H5)3P]2Pd(CH3COO)2 and a molecular weight of 749.08 g/mol. This catalyst is widely employed in organic synthesis for facilitating crucial carbon-carbon bond formations. It is a valuable reagent for various coupling reactions, making it indispensable in pharmaceutical and fine chemical manufacturing.

IUPAC
Bis(acetato)bis(triphenylphosphine)palladium(II),Palladium(II)bis(triphenylphosphine) diacetate,Pd(OAc)2(PPh3)2
Synonyms
Bis(acetato)bis(triphenylphosphine)palladium(II)Palladium(II)bis(triphenylphosphine) diacetatePd(OAc)2(PPh3)2
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Bis(triphenylphosphine)palladium(II) diacetate ([(C6H5)3P]2Pd(CH3COO)2) — chemical structure, CAS 14588-08-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisHomogeneous Pd CatalystsPalladium
01 /Applications

Sonogashira Coupling Reactions

This compound serves as an effective catalyst for the Sonogashira coupling, a reaction that forms carbon-carbon bonds by coupling terminal alkynes with aryl or vinyl halides. It enables the synthesis of complex organic molecules.

Negishi Coupling Reactions

Bis(triphenylphosphine)palladium(II) diacetate is utilised in Negishi coupling, a cross-coupling reaction between organozinc compounds and organohalides or pseudohalides. This facilitates the formation of C-C bonds with high functional group tolerance.

Heck Coupling Reactions

The diacetate is an active catalyst in Heck coupling reactions, which involve the palladium-catalyzed coupling of aryl or vinyl halides with olefins. This is a fundamental tool for constructing substituted alkenes.

Suzuki Coupling Reactions

This palladium complex is employed as a catalyst in Suzuki coupling, a versatile reaction for forming carbon-carbon bonds between organoboron compounds and organohalides or pseudohalides. It is extensively used in drug discovery and materials science.

02 /Properties
Molecular weight749.08
Linear formula[(C6H5)3P]2Pd(CH3COO)2
Assay98%
ApplicationCatalyst for C-C bond formation via Sonogashira coupling, Negishi coupling, Heck coupling, and Suzuki coupling reaction.
Melting point136 °C (dec.)(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
14588-08-0
MDL number
MFCD00010013
PubChem substance
24853498
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Bis(triphenylphosphine)palladium(II) diacetate used for?

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Bis(triphenylphosphine)palladium(II) diacetate is primarily used as a catalyst in various palladium-catalyzed cross-coupling reactions, including Sonogashira, Negishi, Heck, and Suzuki couplings, for the formation of carbon-carbon bonds.

What is the CAS number and formula for Bis(triphenylphosphine)palladium(II) diacetate?

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The CAS number is 14588-08-0, and its linear formula is [(C6H5)3P]2Pd(CH3COO)2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Bis(triphenylphosphine)palladium(II) diacetate with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations for handling this compound?

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This compound is a palladium complex and should be handled with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) is recommended. It has a WGK Germany rating of 3, indicating it is hazardous to water.

How is Bis(triphenylphosphine)palladium(II) diacetate packed and shipped?

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As a specialist global supplier, Tech Serve Solutions exports chemicals worldwide, ensuring appropriate packaging and adherence to shipping regulations for safe transport.

How can I request a quote or sample?

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To request a quote or sample of Bis(triphenylphosphine)palladium(II) diacetate, please contact our sales team through the website or by phone.

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