Bis(pentafluorophenyl) carbonate
Bis(pentafluorophenyl) carbonate (CAS 59483-84-0) is a reactive organic compound with the linear formula (C6F5O)2CO and a molecular weight of 394.12 g/mol. It is characterised by its activated carbonate structure, making it a valuable reagent in organic synthesis. Its primary applications include its use as an activating agent in peptide synthesis and for the formation of active esters in various chemical transformations.
- IUPAC
- Pentafluorophenyl carbonate
- Synonyms
- Pentafluorophenyl carbonate
Peptide Synthesis Reagent
Bis(pentafluorophenyl) carbonate serves as an efficient coupling reagent in peptide synthesis. It facilitates the formation of peptide bonds by activating carboxylic acids for reaction with amines, enabling the construction of peptide chains.
Active Ester Formation
This compound is utilised for the synthesis of activated esters, particularly pentafluorophenyl esters. These active esters are useful intermediates in acylation reactions and can be readily displaced by nucleophiles like amines and alcohols.
Chemical Biology Applications
In chemical biology, Bis(pentafluorophenyl) carbonate can be employed in the modification of biomolecules. Its reactivity allows for the introduction of specific functional groups or labels onto proteins and other biological structures.
General Organic Synthesis
Beyond specific applications, it functions as a versatile activating agent in general organic synthesis for forming carbonate and carbamate linkages, contributing to the construction of complex organic molecules.
| Molecular weight | 394.12 |
|---|---|
| Linear formula | (C6F5O)2CO |
| Assay | 97% |
| Melting point | 47-50 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(pentafluorophenyl) carbonate used for?
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Bis(pentafluorophenyl) carbonate is primarily used as an activating agent in peptide synthesis and for the formation of active esters in organic chemistry. It is also applied in chemical biology for biomolecule modification.
What is the CAS number and formula for Bis(pentafluorophenyl) carbonate?
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The CAS number is 59483-84-0 and the linear formula is (C6F5O)2CO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(pentafluorophenyl) carbonate with an assay of 97%. This product is intended for research and laboratory use, and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the key safety considerations when handling Bis(pentafluorophenyl) carbonate?
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Handling Bis(pentafluorophenyl) carbonate requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It has a flash point of 110 °C (230 °F).
How is Bis(pentafluorophenyl) carbonate packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packing for Bis(pentafluorophenyl) carbonate according to international shipping regulations. We handle export logistics for customers worldwide.
How can I request a quote or sample of Bis(pentafluorophenyl) carbonate?
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To request a quote or a sample of Bis(pentafluorophenyl) carbonate, please contact our sales department through the website or by phone, providing your specific requirements.
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