1-Benzyl-3-oxopiperazine
1-Benzyl-3-oxopiperazine (CAS: 13754-41-1; Formula: C11H14N2O; MW: 190.24) is a heterocyclic building block used in chemical synthesis. It serves as a key intermediate, notably in copper-catalyzed amidation reactions with aryl bromides. This compound is supplied by TSS with an assay of 95%, suitable for research and development purposes. Its piperazine core makes it valuable for constructing more complex molecular architectures.
- IUPAC
- 4-(Phenylmethyl)-2-piperazinone
Amidation Reactions
Utilised in copper-catalyzed amidation of aryl bromides, facilitating the formation of carbon-nitrogen bonds.
Heterocyclic Synthesis
Serves as a versatile building block for synthesising complex heterocyclic compounds, particularly those containing piperazine motifs.
Organic Synthesis Intermediate
Employed in various organic synthesis pathways as a crucial intermediate for developing novel chemical entities.
| Molecular weight | 190.24 |
|---|---|
| Empirical formula | C11H14N2O |
| Assay | 95% |
| Application | Used in a copper-catalyzed amidation of an aryl bromide.1 |
| Melting point | 148-155 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Benzyl-3-oxopiperazine used for?
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1-Benzyl-3-oxopiperazine is primarily used as a building block in organic synthesis, particularly in copper-catalyzed amidation reactions of aryl bromides and the construction of complex heterocyclic structures.
What is the CAS number and formula for 1-Benzyl-3-oxopiperazine?
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The CAS number is 13754-41-1 and the empirical formula (Hill notation) is C11H14N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Benzyl-3-oxopiperazine with an assay of 95%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 1-Benzyl-3-oxopiperazine be handled safely?
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1-Benzyl-3-oxopiperazine is classified as harmful if swallowed and causes skin, eye, and respiratory irritation (H302-H315-H319-H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is 1-Benzyl-3-oxopiperazine exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Benzyl-3-oxopiperazine.
How can I request a sample or quote for 1-Benzyl-3-oxopiperazine?
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Please contact our sales team via the website or by telephone to request a sample or a quotation for 1-Benzyl-3-oxopiperazine.
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