Benzyl ether
Benzyl ether (CAS 103-50-4), with the linear formula (C6H5CH2)2O and a molecular weight of 198.26 g/mol, is an organic compound belonging to the ether family. It is recognised for its utility as a solvent and a building block in chemical synthesis. Notably, Benzyl ether has found application in biological research as an effective tissue-clearing medium for imaging applications, demonstrating its versatility beyond traditional chemical uses.
- IUPAC
- Dibenzyl ether
- Synonyms
- Dibenzyl ether
Tissue Clearing Medium
Benzyl ether has been employed as a GFP-friendly medium for clearing mouse brains, facilitating advanced 3D imaging of biological tissues. Its properties allow for detailed microscopic analysis of solvent-cleared organs.
Chemical Synthesis
As an organic building block, Benzyl ether is utilised in various chemical synthesis pathways. Its ether structure lends itself to reactions common in organic chemistry, contributing to the creation of more complex molecules.
Solvent Applications
Possessing miscibility with common organic solvents such as acetone, chloroform, and ethanol, Benzyl ether can function as a solvent in specific laboratory and industrial processes.
| Molecular weight | 198.26 |
|---|---|
| Linear formula | (C6H5CH2)2O |
| Assay | 98% |
| Boiling point | 298 °C(lit.) |
| Density | 1.043 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.561(lit.) |
| Solubility | H2O: insolubleacetone: misciblechloroform: misciblediethyl ether: miscibleethanol: miscible |
| Melting point | 1.5-3.5 °C(lit.) |
| Application | Benzyl ether was used as an effective GFP friendly tissue clearing medium for mouse brains1. It was used in a study to develop a detailed protocol for performing 3D imaging of solvent-cleared organs and its application to various microscopy techniques2. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 135 °C / 275 °F |
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 36/37/38-51/53 |
| Safety statements (S) | 23-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzyl ether primarily used for?
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Benzyl ether (CAS 103-50-4) is used in chemical synthesis and has been identified as an effective tissue-clearing medium for biological imaging studies.
What are the CAS number and formula for Benzyl ether?
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The CAS number for Benzyl ether is 103-50-4, and its linear formula is (C6H5CH2)2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Benzyl ether with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Benzyl ether be handled safely?
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Benzyl ether is classified with H-statements H315 (causes skin irritation), H319 (causes serious eye irritation), H335 (may cause respiratory irritation), and H411 (toxic to aquatic life with long lasting effects). Appropriate personal protective equipment, including eyeshields and gloves, should be used. Handle in a well-ventilated area, and avoid release into the environment.
Is Benzyl ether a controlled substance?
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Based on the provided data, Benzyl ether is not listed as a controlled substance. However, users should always verify local regulations.
How is Benzyl ether packed and shipped by TSS?
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Benzyl ether is supplied in appropriate packaging for chemical transport and is exported globally by Tech Serve Solutions in compliance with international shipping regulations.
How can I request a sample or quote for Benzyl ether?
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To request a sample or a quote for Benzyl ether, please contact the Tech Serve Solutions sales team via our website or listed contact information.
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