BAY 73-6691
BAY 73-6691 (CAS: 794568-92-6) is an organic compound with the molecular formula C15H12ClF3N4O and a molecular weight of 356.73 g/mol. Supplied as an off-white powder, this chemical is primarily utilised in research settings for its role in cell signalling and neuroscience, particularly as a phosphodiesterase inhibitor. Its applications extend to studying cyclic nucleotide metabolism and G protein pathways.
- IUPAC
- 1-(2-Chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-one

Phosphodiesterase Inhibition Research
BAY 73-6691 serves as a valuable tool for researchers investigating the mechanisms of phosphodiesterase (PDE) enzymes. Its inhibitory activity is instrumental in understanding cellular signalling pathways regulated by cyclic nucleotides.
Cellular Signalling Studies
This compound aids in the exploration of complex cellular signalling cascades. It is particularly relevant for studies in neuroscience and cell biology due to its impact on intracellular second messenger systems.
Cyclic Nucleotide Metabolism
Researchers utilise BAY 73-6691 to probe the metabolic pathways of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Understanding these pathways is crucial for various physiological processes.
G Protein Signalling Research
The compound is employed in studies focusing on G protein-coupled receptors (GPCRs) and downstream signalling events. Its effects on cyclic nucleotide levels can influence these pathways.
| Molecular weight | 356.73 |
|---|---|
| Empirical formula | C15H12ClF3N4O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,Xi |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is BAY 73-6691 used for?
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BAY 73-6691 is used in research for studying phosphodiesterase inhibition, cellular signalling, cyclic nucleotide metabolism, and G protein pathways, particularly in neuroscience and cell biology.
What are the CAS number and molecular formula for BAY 73-6691?
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The CAS number for BAY 73-6691 is 794568-92-6, and its molecular formula is C15H12ClF3N4O.
What grade and purity does Tech Serve Solutions supply for BAY 73-6691?
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Tech Serve Solutions supplies BAY 73-6691 with an assay of ≥98% by HPLC. We do not represent this product as meeting any pharmacopoeia standards such as USP, BP, or EP.
How should BAY 73-6691 be handled safely?
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BAY 73-6691 is classified with Danger signal word and has hazards including acute toxicity (H300), skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge, in a well-ventilated area. Refer to the safety data sheet for full details.
Is BAY 73-6691 a controlled substance?
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The provided data does not indicate that BAY 73-6691 is a controlled substance.
How is BAY 73-6691 shipped and exported?
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BAY 73-6691 is shipped according to its UN classification UN 2811, Hazard Class 6.1, Packing Group III. Tech Serve Solutions is experienced in global export of fine chemicals.
How can I request a quote or sample for BAY 73-6691?
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To request a quote or sample for BAY 73-6691, please contact our sales team through the website or direct contact details provided by TSS.
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