Arachidonoylserotonin
Arachidonoylserotonin (CAS: 187947-37-1), with the molecular formula C30H42N2O2 and a molecular weight of 462.67 g/mol, is a compound primarily utilised in research settings. It functions as a fatty acid amide hydrolase (FAAH) inhibitor and a transient receptor potential vanilloid-type I (TRPV1) antagonist. These properties make it a valuable tool for investigating pain pathways and neurological processes.
- IUPAC
- AA-5-HT,N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenamide
- Synonyms
- AA-5-HT,N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenamide

Research into Pain Management
Arachidonoylserotonin's role as an FAAH inhibitor and TRPV1 antagonist makes it a key compound for studying the endocannabinoid system and its involvement in pain signalling pathways. It aids in understanding potential therapeutic targets for chronic pain conditions.
Neurobiology and Neuroscience Studies
This compound has been employed in research to explore the mechanisms of cortical plasticity following peripheral nerve injury. Its interaction with endovanilloid pathways offers insights into neuronal adaptation and recovery.
Cell Biology and Signaling Research
As a bioactive small molecule, Arachidonoylserotonin is utilised to investigate cellular responses and signalling cascades, particularly those modulated by fatty acid amides and related receptors.
| Molecular weight | 462.67 |
|---|---|
| Empirical formula | C30H42N2O2 |
| Assay | ≥98% (HPLC) |
| Form | oil |
| Colour | yellow |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | −20°C |
| Application | Arachidonoylserotonin is a fatty acid amide hydrolase (FAAH) inhibitor and transient receptor potential vanilloid-type I (TRPV1) antagonist. Both FAAH and TRPV1 are targets for chronic pain treatment. Arachidonoylserotonin has been used in a study to determine the involvement of endovanilloids in the cortical plastic changes associated with peripheral nerve injury. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Arachidonoylserotonin used for?
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Arachidonoylserotonin is primarily used in research to study pain pathways, neurobiology, and cell signaling, due to its activity as a fatty acid amide hydrolase (FAAH) inhibitor and transient receptor potential vanilloid-type I (TRPV1) antagonist.
What is the CAS number and formula for Arachidonoylserotonin?
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The CAS number for Arachidonoylserotonin is 187947-37-1, and its empirical formula is C30H42N2O2.
What grade and purity does Tech Serve Solutions supply for Arachidonoylserotonin?
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Tech Serve Solutions supplies Arachidonoylserotonin with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.
What are the safety considerations for handling Arachidonoylserotonin?
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When handling Arachidonoylserotonin, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with WGK Germany 3, indicating a high hazard to water.
How is Arachidonoylserotonin shipped and stored?
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Arachidonoylserotonin is shipped on wet ice and should be stored at -20°C to maintain its stability and integrity.
How can I request a quote or sample for Arachidonoylserotonin?
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To request a quote or sample for Arachidonoylserotonin, please contact our sales team through the TSS website or by phone.
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