(±)-Anabasine
(±)-Anabasine (CAS: 13078-04-1), a chemical compound with the formula C10H14N2 and a molecular weight of 162.23 g/mol, presents as a colorless to yellow liquid. It is recognized for its biological activity, particularly as a nicotinic acetylcholine receptor agonist. This compound serves as a valuable tool in neuroscience research, cell biology studies, and as a reference standard in analytical chemistry, contributing to a deeper understanding of receptor function and related physiological processes.
- IUPAC
- 3-(2-Piperidinyl)pyridine,Neonicotine
Neuroscience Research
(±)-Anabasine is utilised as a pharmacological tool to investigate the function of nicotinic acetylcholine receptors (nAChRs) in the central and peripheral nervous systems. Its agonistic properties allow researchers to probe receptor subtypes and their roles in neurotransmission.
Chemical Synthesis
As a heterocyclic building block, (±)-Anabasine can be employed in the synthesis of more complex organic molecules. Its structure, featuring a pyridine and a piperidine ring, offers versatile reactivity for developing novel chemical entities.
Analytical Standards
This compound serves as a reference standard in analytical and chromatographic applications. Its availability as a well-characterized substance is crucial for method development, validation, and quality control in various analytical settings.
Cell Biology Studies
Due to its specific interactions with nAChRs, (±)-Anabasine is applied in cell-based assays to study cellular responses mediated by these receptors. This aids in understanding signaling pathways and cellular functions influenced by cholinergic systems.
| Molecular weight | 162.23 |
|---|---|
| Empirical formula | C10H14N2 |
| Assay | ≥90% (TLC) |
| Form | liquid |
| Colour | colorless to yellow |
| Density | 1.05 g/mL at 25 °C(lit.) |
| Solubility | H2O: soluble10 mg/mLethanol: soluble50 mg/mL |
| Optical activity | [α]25/D 0°, c = 1 in H2O(lit.) |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 93 °C / 199.4 °F |
| Transport (UN / ADR) | UN 3140 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Chrna7(11441), Chrnb1(11443) |
|---|---|
| Transition Temp | freezing point 9 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-Anabasine used for?
+
(±)-Anabasine is used in neuroscience research to study nicotinic acetylcholine receptors, in chemical synthesis as a building block, and as an analytical standard for chromatographic and other analytical methods. It is also utilized in cell biology studies related to receptor function.
What is the CAS number and formula for (±)-Anabasine?
+
The CAS number for (±)-Anabasine is 13078-04-1, and its chemical formula is C10H14N2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (±)-Anabasine with an assay of ≥90% (TLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How is (±)-Anabasine handled and what are the safety concerns?
+
(±)-Anabasine is a Danger signal word compound with hazards including acute toxicity (oral) and skin/eye irritation. Appropriate personal protective equipment such as eyeshields, gloves, and respirators should be used. Handle in a well-ventilated area.
Is (±)-Anabasine shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (±)-Anabasine.
How can I request a quote or sample for (±)-Anabasine?
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To request a quote or sample for (±)-Anabasine, please contact the Tech Serve Solutions sales team through our website or by phone.
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