(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (CAS 53188-07-1), with the empirical formula C14H18O4 and a molecular weight of 250.29, is a chemical compound utilized in various research applications. It is particularly recognised for its role in antioxidant assays, serving as a standard for determining the total antioxidant capacity of different substances. This compound is supplied by Tech Serve Solutions for laboratory and research purposes.
- IUPAC
- Trolox
- Synonyms
- Trolox(±)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid8-tetramethylchromane-2-carboxylic acid

Antioxidant Assays (TEAC)
This compound, also known as Trolox, is a key component in the Trolox Equivalent Antioxidant Capacity (TEAC) assay. This assay is widely used to measure the total antioxidant capacity of various substances, including those found in fruit species.
Chemical Synthesis Building Block
As a heterocyclic building block, it can be employed in synthetic organic chemistry for the construction of more complex molecules. Its specific chemical structure offers potential for diverse derivatisation.
Cell Biology Research
The compound's antioxidant properties make it relevant for studies in cell biology, particularly in investigations concerning oxidative stress and cellular protection mechanisms. It can be used to explore the effects of antioxidants at a cellular level.
| Molecular weight | 250.29 |
|---|---|
| Empirical formula | C14H18O4 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) has been used in 6-hydroxy-2,5,7,8-tetramethyl chromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to determine the total antioxidant capacity of different fruit species1. |
| Melting point | 187-189 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Akr1b1(24192) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid used for?
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This compound is primarily used as a standard in antioxidant capacity assays, such as the TEAC assay, and as a building block in chemical synthesis and cell biology research.
What is the CAS number and molecular formula for this chemical?
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The CAS number is 53188-07-1, and the empirical formula is C14H18O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for this product?
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This compound is a warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is recommended to wear eyeshields, gloves, and a dust mask type N95 (US). Handle in a well-ventilated area.
How is this product typically packed and exported?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all relevant shipping regulations for safe transit.
How can I request a sample or a quote for this chemical?
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To request a sample or a quote, please use the 'Request a Quote' or 'Sample Request' functions on our website, or contact our sales team directly.
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