Alamethicin from Trichoderma viride
Alamethicin from Trichoderma viride (CAS: 27061-78-5) is a cyclic peptide antibiotic known for its ability to form pores in lipid bilayers. This monovalent cation ionophore mimics nerve action potentials and is valuable in biophysical studies of membrane permeability. It is also employed in investigating the membrane interactions of antimicrobial peptides, serving as a key reagent in cell biology and membrane research.
- IUPAC
- Antibiotic U-22324
Ionophore Studies
Alamethicin functions as a monovalent cation ionophore, capable of creating transmembrane pores. This property allows it to mimic nerve action potentials across artificial lipid membranes, making it a valuable tool for electrophysiological research.
Antimicrobial Peptide Research
The compound is utilized to study the mechanisms by which antimicrobial peptides interact with and perturb cell membranes. Its well-defined pore-forming activity provides a model system for understanding these complex interactions.
Cell Membrane Permeability
Alamethicin is employed to investigate alterations in cell membrane permeability. Its ability to form voltage-gated channels makes it useful for studying ion transport and its effects on cellular function.
| Assay | ≥98% (HPLC) |
|---|---|
| Storage temperature | 2-8°C |
| Application | Alamethicin is a monovalent cation ionophore which can mimic nerve action potential across artificial membranes. Alamethicin has also been used to study membrane interactions of antimicrobial peptides. |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Alamethicin from Trichoderma viride used for?
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Alamethicin is used as a monovalent cation ionophore to mimic nerve action potentials across artificial membranes and to study membrane interactions of antimicrobial peptides, making it valuable in biophysics and cell biology research.
What are the CAS number and formula for Alamethicin?
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The CAS number for Alamethicin from Trichoderma viride is 27061-78-5. The molecular formula is not specified in the provided data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Alamethicin from Trichoderma viride at a PREMIUM quality level with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Alamethicin be handled safely?
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Alamethicin is classified as Danger (GHS06) and is toxic if swallowed (H301). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. In case of accidental ingestion, seek immediate medical attention (P301 + P310).
How is Alamethicin packed and shipped?
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Alamethicin requires storage at 2-8°C. As per RIDADR UN 3462 6.1 / PGIII, it is shipped as a toxic solid.
How can I request a sample or quote for Alamethicin?
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To request a sample or a quote for Alamethicin, please contact our sales team through our website or by phone.
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