Aflatoxin B1 from Aspergillus flavus
Aflatoxin B1 (CAS: 1162-65-8; C17H12O6; MW: 312.27) is a potent, naturally occurring mycotoxin produced by certain strains of Aspergillus fungi, notably Aspergillus flavus. This PREMIUM grade compound is primarily used in scientific research as a reference standard for detecting aflatoxin contamination in food products. Its significant carcinogenic properties also make it a valuable tool for studying DNA damage and cancer mechanisms, particularly its role in inducing mutations in the p53 tumour suppressor gene.
Food Safety Testing
Aflatoxin B1 serves as a crucial internal standard for analytical methods designed to detect and quantify aflatoxin contamination in various food commodities, ensuring regulatory compliance and consumer safety.
Carcinogenesis Research
This mycotoxin is extensively used in toxicological and cancer research to investigate the molecular mechanisms of chemical carcinogenesis, particularly its known genotoxicity and induction of G to T transversion mutations in the p53 gene.
Biochemical Studies
As a well-characterised bioactive small molecule, Aflatoxin B1 is utilised in biochemical assays to study enzyme inhibition, DNA adduct formation, and cellular responses to toxic compounds.
| Molecular weight | 312.27 |
|---|---|
| Empirical formula | C17H12O6 |
| Assay | ≥98% (TLC and HPLC) |
| Storage temperature | 2-8°C |
| Application | Aflatoxin B1 is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. Aflatoxin B1 may be used as an internal standard when testing for aflatoxin contamination in food products. |
| Biological source | from Aspergillus flavus |
Hazard statements
- H300Fatal if swallowed
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3462 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 45-46-26/27/28 |
| Safety statements (S) | 53-28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Aflatoxin B1 used for?
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Aflatoxin B1 is primarily used in scientific research as a reference standard for testing food contamination and in studies investigating its carcinogenic and genotoxic effects, particularly its role in p53 gene mutations.
What are the CAS and formula for Aflatoxin B1?
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The CAS number for Aflatoxin B1 is 1162-65-8, and its empirical formula is C17H12O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Aflatoxin B1 at PREMIUM grade with an assay of ≥98% (TLC and HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Aflatoxin B1 be handled safely?
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Aflatoxin B1 is highly toxic and carcinogenic (H300 + H310 + H330, H350). Handle with extreme caution using appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator. Ensure adequate ventilation and follow strict laboratory safety protocols to avoid inhalation, ingestion, and skin contact.
Is Aflatoxin B1 a controlled substance?
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Aflatoxin B1 is not listed as a controlled substance under international drug control conventions. However, due to its high toxicity and carcinogenicity, its handling and use are subject to strict regulations in research and laboratory settings.
How is Aflatoxin B1 packed, shipped, and exported?
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Aflatoxin B1 is carefully packed according to international shipping regulations for hazardous materials. As a global supplier, Tech Serve Solutions professionally handles all export documentation and logistics to ensure compliant and secure delivery worldwide.
How can I request a sample or quote for Aflatoxin B1?
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To request a sample or a quotation for Aflatoxin B1, please contact our sales team via the website's inquiry form or by direct email, providing your contact details and intended application.
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