AdBrettPhos
AdBrettPhos (CAS: 1160861-59-5), a phosphine compound with the molecular formula C43H61O2P and a molecular weight of 640.92, is a valuable reagent in modern organic synthesis. This Buchwald ligand is primarily employed in palladium-catalysed cross-coupling reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds with high efficiency and selectivity. Its application is crucial in the synthesis of complex molecules across various chemical industries.
- IUPAC
- Di-Ad-BrettPhos
- Synonyms
- Di-Ad-BrettPhos
Palladium-Catalyzed Cross-Coupling Reactions
AdBrettPhos serves as a key ligand in numerous palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig amination, and Sonogashira couplings. It enhances catalyst activity and stability, enabling efficient bond formation.
Organic Synthesis
This phosphine ligand is instrumental in the construction of intricate molecular architectures. It is widely used in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.
Catalysis Research
As a specialized Buchwald ligand, AdBrettPhos is frequently utilised in academic and industrial research settings to develop new synthetic methodologies and explore novel catalytic transformations.
| Molecular weight | 640.92 |
|---|---|
| Empirical formula | C43H61O2P |
| Assay | 95% |
| Melting point | 231-235 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is AdBrettPhos used for?
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AdBrettPhos is primarily used as a ligand in palladium-catalyzed cross-coupling reactions to facilitate the formation of carbon-carbon and carbon-heteroatom bonds in organic synthesis.
What is the CAS number and molecular formula for AdBrettPhos?
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The CAS number for AdBrettPhos is 1160861-59-5, and its molecular formula is C43H61O2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies AdBrettPhos with a minimum purity of 95%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for AdBrettPhos?
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AdBrettPhos is classified as hazardous. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed hazard information and handling procedures. It has a Water Hazard Class (WGK) of 3 in Germany.
How is AdBrettPhos packed and shipped?
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AdBrettPhos is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.
How can I request a quote or sample of AdBrettPhos?
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To request a quote or sample of AdBrettPhos, please contact our sales team through the website or by phone, providing your specific requirements.
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