Acemetacin
Acemetacin (CAS 53164-05-9), with the empirical formula C21H18ClNO6 and a molecular weight of 415.82 g/mol, is a non-steroidal anti-inflammatory drug (NSAID) that acts as a prodrug. It is metabolised in the body to indomethacin, sulindac, and other active metabolites. Acemetacin is primarily used for its anti-inflammatory, analgesic, and antipyretic properties in the management of various inflammatory and pain conditions.
- IUPAC
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid carboxymethyl ester
- Synonyms
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid carboxymethyl ester
Pharmaceutical Intermediate
Acemetacin serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its structure allows for further chemical modification to develop novel drug candidates or to produce existing active pharmaceutical ingredients (APIs).
Research Chemical
As a well-characterised compound, Acemetacin is utilised in research laboratories for pharmacological studies. It aids in understanding drug metabolism, mechanism of action of NSAIDs, and the development of new therapeutic agents.
Analytical Standard
This compound is employed as an analytical standard for quality control and quantitative analysis in pharmaceutical manufacturing and research. It ensures the accuracy and reliability of testing procedures for related substances.
| Molecular weight | 415.82 |
|---|---|
| Empirical formula | C21H18ClNO6 |
| Grade | analytical standard |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28 |
| Safety statements (S) | 22-25-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acemetacin used for?
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Acemetacin is used for its anti-inflammatory, analgesic, and antipyretic properties in managing inflammatory and pain conditions. It also serves as a pharmaceutical intermediate and an analytical standard in research and manufacturing.
What are the CAS number and formula for Acemetacin?
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The CAS number for Acemetacin is 53164-05-9, and its empirical formula is C21H18ClNO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Acemetacin as an analytical standard. The specific purity and assay are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should Acemetacin be handled?
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Acemetacin is classified as acutely toxic. Handle with extreme caution, using appropriate personal protective equipment including eyeshields, face shields, gloves, and a full-face particle respirator (type N100 US or P3 EN143). Ensure adequate ventilation and avoid dust formation.
How is Acemetacin packed and shipped?
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Acemetacin is packaged in compliance with international regulations for hazardous materials. It is shipped and exported globally by Tech Serve Solutions adhering to all necessary safety and transport guidelines for toxic substances (UN 2811, 6.1, PGII).
How can I request a quote or sample for Acemetacin?
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To request a quote or a sample of Acemetacin, please contact the Tech Serve Solutions sales team through our website or by calling our main office. Our team will assist you with your inquiry promptly.
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