8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt (CAS: 51239-26-0) is a bioactive small molecule with a molecular weight of 509.79 g/mol. This guanosine analog, typically supplied as a white powder, is primarily utilised in biochemical research. Its applications often involve studying cyclic nucleotide metabolism, cell signalling pathways, and protein kinase activity, particularly Protein Kinase G (PKG).
- IUPAC
- 8-pCPT-cGMP,pCPT-cGMP
- Synonyms
- 8-pCPT-cGMPpCPT-cGMP
Cell Signaling Research
This compound serves as a valuable tool for investigating cellular signalling cascades, particularly those involving cyclic nucleotides like cGMP. Researchers use it to probe the intricate mechanisms of signal transduction within cells.
Enzyme Activity Studies
It is employed in studies focused on the activity of kinases and phosphatases, such as Protein Kinase G (PKG). Its structural similarity to natural cGMP allows for competitive inhibition or activation studies.
Neuroscience Research
Given the role of cyclic nucleotides in neuronal function, this guanosine analog can be utilised in neuroscience research to understand neurotransmission and related cellular processes.
Drug Discovery and Development
As a bioactive small molecule, it may be used in early-stage drug discovery efforts to explore potential therapeutic targets related to pathways it modulates.
| Molecular weight | 509.79 |
|---|---|
| Empirical formula | C16H14ClN5NaO7PS |
| Assay | ~95% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble25 mg/mL |
| Storage temperature | −20°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt used for?
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This compound is primarily used in biochemical and cell biology research to study cyclic nucleotide metabolism, cell signalling, and the activity of enzymes like Protein Kinase G (PKG).
What are the CAS number and formula for this compound?
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The CAS number is 51239-26-0. The empirical formula (Hill Notation) is C16H14ClN5NaO7PS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ~95% (HPLC). It is supplied as a technical/research grade material and TSS does not represent it as USP/BP/EP.
What are the safety and handling considerations?
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This compound has a WGK Germany rating of 3, indicating it is hazardous. Handle with appropriate personal protective equipment in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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This product is typically supplied as a white powder and stored at -20°C. TSS exports fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or a quote?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for this product.
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