7-(Trifluoromethyl)quinoline-4-thiol
7-(Trifluoromethyl)quinoline-4-thiol (CAS: 64415-07-2; Formula: C10H6F3NS; Molar Mass: 229.22 g/mol) is a heterocyclic organic compound. This chemical serves as a valuable building block in synthetic organic chemistry. Its structure, featuring a quinoline core with a trifluoromethyl group and a thiol substituent, makes it suitable for various research and development applications, particularly in medicinal chemistry and materials science.

Investigation of Lipid Metabolism
7-(Trifluoromethyl)quinoline-4-thiol has been employed in studies to elucidate the mechanisms by which lipid-poor particles are generated from high-density lipoprotein, a process influenced by cholesteryl ester transfer protein.
Synthetic Organic Chemistry
As a functionalized quinoline derivative, this compound acts as a key intermediate in the synthesis of more complex organic molecules, offering a scaffold for further chemical modification in research settings.
Research and Development
The unique trifluoromethyl and thiol functionalities position this molecule for use in various R&D projects, including the exploration of novel pharmaceutical agents and functional materials.
| Molecular weight | 229.22 |
|---|---|
| Empirical formula | C10H6F3NS |
| Assay | 95% |
| Application | 7-(Trifluoromethyl)quinoline-4-thiol was used to investigate the mechanism of generation of lipid-poor particles from high-density lipoprotein induced by cholesteryl ester transfer protein1. |
| Melting point | 222-225 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-(Trifluoromethyl)quinoline-4-thiol used for?
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This compound is primarily used as a building block in synthetic organic chemistry and in research investigating lipid metabolism mechanisms.
What are the CAS number and formula for 7-(Trifluoromethyl)quinoline-4-thiol?
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The CAS number is 64415-07-2, and the chemical formula is C10H6F3NS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 7-(Trifluoromethyl)quinoline-4-thiol with an assay of 95%. This is a research-grade chemical and is not supplied as USP, BP, or EP grade.
What are the primary safety concerns when handling this chemical?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (NIOSH N95), eyeshields, and gloves, should be used.
How is this chemical supplied and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 7-(Trifluoromethyl)quinoline-4-thiol, which is carefully packed and shipped to meet international standards.
How can I request a sample or quote for 7-(Trifluoromethyl)quinoline-4-thiol?
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To request a sample or a quotation for 7-(Trifluoromethyl)quinoline-4-thiol, please contact the Tech Serve Solutions sales team through our website or by phone.
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