7-Methylindole
7-Methylindole (CAS 933-67-5, C9H9N, MW 131.17) is a valuable heterocyclic building block for chemical synthesis. This indole derivative serves as a key reactant in the preparation of diverse organic compounds. Its applications range from the development of potential anticancer immunomodulators and antifungal agents to plant growth inhibitors and treatments for hyperglycemia, making it a versatile intermediate in pharmaceutical and agrochemical research.
- IUPAC
- NSC 618
Pharmaceutical Intermediate
7-Methylindole is utilized in the synthesis of various pharmaceutically relevant compounds, including pyrrolidine analogues, tryptophan dioxygenase inhibitors with potential anticancer activity, and SGLT2 inhibitors for diabetes management.
Agrochemical Synthesis
This compound acts as a reactant for developing plant growth inhibitors and antifungal agents, contributing to advancements in crop protection and agricultural chemistry.
Organic Synthesis Reactant
It serves as a substrate in fundamental organic reactions such as Friedel-Crafts alkylation and reductive formylation, enabling the construction of complex molecular architectures.
HIV-1 Inhibitor Research
7-Methylindole is employed in the synthesis pathways aimed at developing inhibitors that target HIV-1 attachment, contributing to antiviral research efforts.
| Molecular weight | 131.17 |
|---|---|
| Empirical formula | C9H9N |
| Assay | 97% |
| Boiling point | 266 °C(lit.) |
| Application | Reactant for preparation of:• Pharmaceutically active pyrrolidine analogues via Markovnikov addition1• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• Plant growth inhibitors3• Antifungal agents4• Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes5• Inhibitors of HIV-1 attachment6Reactant for:• Friedel-Crafts alkylation reactions7• Reductive formylation reactions8 |
| Melting point | 80-84 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary applications of 7-Methylindole?
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7-Methylindole is primarily used as a reactant in the preparation of pharmaceutically active compounds like pyrrolidine analogues, tryptophan dioxygenase inhibitors, and SGLT2 inhibitors. It is also employed in the synthesis of plant growth inhibitors, antifungal agents, and inhibitors of HIV-1 attachment, as well as in Friedel-Crafts alkylation and reductive formylation reactions.
What are the CAS number and chemical formula for 7-Methylindole?
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The CAS number for 7-Methylindole is 933-67-5, and its chemical formula is C9H9N.
What grade and purity does Tech Serve Solutions supply for 7-Methylindole?
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Tech Serve Solutions supplies 7-Methylindole with an assay of 97%. This product is suitable for research and chemical synthesis purposes. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 7-Methylindole be handled safely?
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7-Methylindole is classified with the GHS07 symbol and carries a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area and follow precautionary statements P261 and P305 + P351 + P338.
How is 7-Methylindole supplied and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 7-Methylindole. Products are carefully packed and exported according to international shipping regulations.
How can I request a sample or quote for 7-Methylindole?
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To request a sample or a quote for 7-Methylindole, please contact the Tech Serve Solutions sales department through our official website or direct inquiry channels.
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