7-Methylindole-2-carboxylic acid

CAS 18474-60-7C10H9NO2Chemical Synthesis

7-Methylindole-2-carboxylic acid (CAS: 18474-60-7), with the molecular formula C10H9NO2 and a molecular weight of 175.18, is a heterocyclic building block. This compound serves as a key reactant in the synthesis of various complex molecules. Its applications are primarily found in medicinal chemistry research, including the development of receptor antagonists and enzyme inhibitors, making it valuable for pharmaceutical research and chemical synthesis.

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7-Methylindole-2-carboxylic acid (C10H9NO2) — chemical structure, CAS 18474-60-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC10Chemical SynthesisHeterocyclic Building BlocksIndoles

01 /Applications

Preparation of CCK1 Receptor Antagonists

7-Methylindole-2-carboxylic acid is used as a reactant in the synthesis of N-terminal anthranoyl-phenylalanine derivatives that act as CCK1 receptor antagonists.

Synthesis of Factor Xa Inhibitors

This compound serves as a reactant for preparing factor Xa inhibitors, which are based on a 2-carboxyindole scaffold.

Development of Histamine H4 Receptor Antagonists

It is employed as a reactant in the synthesis of potent and selective non-imidazole human histamine H4 receptor antagonists for pharmaceutical research.

02 /Properties

Molecular weight	175.18
Empirical formula	C10H9NO2
Assay	95%
Application	• Reactant for preparation of N-terminal anthranoyl-phenylalanine derivatives as CCK1 receptor antagonists1• Reactant for preparation of factor Xa inhibitors based on a 2-carboxyindole scaffold2• Reactant for preparation of potent and selective non-imidazole human histamine H4 receptor antagonists3
Melting point	169-175 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

18474-60-7

MDL number

MFCD00047168

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 7-Methylindole-2-carboxylic acid used for?

7-Methylindole-2-carboxylic acid is primarily used as a reactant in chemical synthesis and medicinal chemistry research for developing various pharmaceutical compounds, including receptor antagonists and enzyme inhibitors.

What is the CAS number and formula for 7-Methylindole-2-carboxylic acid?

The CAS number for 7-Methylindole-2-carboxylic acid is 18474-60-7, and its molecular formula is C10H9NO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 7-Methylindole-2-carboxylic acid with an assay of 95%. This product is not represented as USP, BP, or EP grade.

How should 7-Methylindole-2-carboxylic acid be handled?

According to GHS, 7-Methylindole-2-carboxylic acid is a Warning substance with hazard statement H319 (Causes serious eye irritation). When handling, wear a dust mask type N95 (US), eyeshields, and gloves. If in eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.