4-Methoxy-2,3,5,6-tetrafluorophenylboronic acid
4-Methoxy-2,3,5,6-tetrafluorophenylboronic acid (CAS 871126-20-4) is a fluorinated aryl boronic acid derivative with the molecular formula C7H5BF4O3 and a molecular weight of 223.92 g/mol. This compound is a valuable building block in organic synthesis, particularly for cross-coupling reactions like Suzuki-Miyaura coupling. Its unique tetrafluorinated phenyl ring offers distinct electronic and steric properties, making it useful in the development of novel pharmaceuticals, agrochemicals, and advanced materials.
- Synonyms
- 6-tetrafluorophenylboronic acid871126-20-4C7H5BF4O3
Suzuki-Miyaura Coupling Reagent
Utilised as a key coupling partner in Suzuki-Miyaura reactions for the synthesis of biaryl compounds. The presence of the tetrafluorophenyl moiety allows for the introduction of fluorinated aromatic systems into target molecules.
Organic Synthesis Intermediate
Serves as a versatile intermediate in complex organic synthesis pathways. Its boronic acid functionality readily participates in various carbon-carbon bond-forming reactions.
Medicinal Chemistry
Incorporated into the design and synthesis of potential drug candidates. Fluorinated aromatic rings can influence pharmacokinetic properties such as metabolic stability and lipophilicity.
Materials Science
Applied in the development of advanced materials, including organic electronics and functional polymers. The electron-withdrawing nature of the fluorine atoms can tune material properties.
| Molecular weight | 223.92 |
|---|---|
| Empirical formula | C7H5BF4O3 |
| Assay | ≥95% |
| Melting point | 144-149 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxy-2,3,5,6-tetrafluorophenylboronic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is valuable in medicinal chemistry and materials science for introducing fluorinated aromatic moieties into target molecules.
What is the CAS number and formula for 4-Methoxy-2,3,5,6-tetrafluorophenylboronic acid?
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The CAS number is 871126-20-4, and the empirical formula (Hill notation) is C7H5BF4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxy-2,3,5,6-tetrafluorophenylboronic acid with an assay of ≥95%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations for handling this chemical?
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4-Methoxy-2,3,5,6-tetrafluorophenylboronic acid is classified under WGK 2 (Water Hazard Class 2). Handle with appropriate personal protective equipment in a well-ventilated area to avoid exposure. Consult the Safety Data Sheet (SDS) for detailed handling and safety information.
How is this product packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations to ensure safe transit. Tech Serve Solutions is an experienced global exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please visit the product page on the Tech Serve Solutions website and use the 'Enquire' or 'Request Quote' function, providing your contact details and requirements.
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