6-Nitro-1,4-benzodioxane
6-Nitro-1,4-benzodioxane (CAS: 16498-20-7), a nitro-substituted benzodioxane derivative with the molecular formula C8H7NO4 and a molecular weight of 181.15 g/mol, is a valuable chemical intermediate. It finds application in various organic synthesis pathways, particularly in the development of novel compounds and research endeavours. Its structural features make it a useful building block for more complex molecules in academic and industrial research settings.
- Synonyms
- C8H7NO4

Organic Synthesis
Serves as a key intermediate in the synthesis of complex organic molecules. Its nitro and benzodioxane functionalities allow for diverse chemical transformations.
Pharmaceutical Research
Utilised as a building block in the discovery and development of new pharmaceutical compounds. It can be incorporated into structures aimed at various therapeutic targets.
Chemical Research and Development
Employed in academic and industrial laboratories for exploring new chemical reactions and developing novel materials. Facilitates the creation of specialised heterocyclic compounds.
| Molecular weight | 181.15 |
|---|---|
| Empirical formula | C8H7NO4 |
| Assay | 97% |
| Melting point | 120-124 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Nitro-1,4-benzodioxane used for?
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6-Nitro-1,4-benzodioxane is primarily used as an intermediate and building block in organic synthesis, with applications in pharmaceutical research and general chemical R&D for creating complex heterocyclic compounds.
What are the CAS number and chemical formula for 6-Nitro-1,4-benzodioxane?
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The CAS number for 6-Nitro-1,4-benzodioxane is 16498-20-7, and its empirical formula (Hill notation) is C8H7NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Nitro-1,4-benzodioxane with an assay of 97%. This is a technical grade suitable for research and chemical synthesis; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling recommendations for 6-Nitro-1,4-benzodioxane?
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Handling 6-Nitro-1,4-benzodioxane requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Observe good laboratory practices and consult the Safety Data Sheet (SDS) for detailed hazard information.
Is 6-Nitro-1,4-benzodioxane a controlled substance?
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Based on the provided data, 6-Nitro-1,4-benzodioxane (CAS: 16498-20-7) is not indicated as a controlled substance.
How is 6-Nitro-1,4-benzodioxane packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals in compliance with all relevant national and international regulations for hazardous materials, ensuring safe and secure transport.
How can I request a sample or quote for 6-Nitro-1,4-benzodioxane?
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To request a sample or a quotation for 6-Nitro-1,4-benzodioxane, please contact the TSS sales department via the website's inquiry form or direct email.
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