6-Methylindole
6-Methylindole (CAS: 3420-02-8, Formula: C9H9N) is a heterocyclic organic compound with a molecular weight of 131.17 g/mol. This indole derivative serves as a valuable building block in chemical synthesis, particularly for the creation of complex molecules with potential biological activities. Its applications span the development of novel pharmaceuticals, including anticancer agents, antifungal compounds, and treatments for diabetes.
Anticancer Agent Precursor
6-Methylindole is utilised as a reactant in the synthesis of pyridyl-ethenyl-indoles, which are investigated as potential immunomodulatory anticancer agents.
Antifungal Compound Synthesis
It serves as a key intermediate in the preparation of indole-linked triazole derivatives and arylsulfonylacylindole derivatives, both classes showing promise as antifungal agents.
Diabetes Management Research
This compound is employed in the synthesis of N-β-D-xylosyl-indole derivatives, which are explored for their potential as SGLT2 inhibitors for managing hyperglycemia in diabetes.
Kinase Inhibitor Development
6-Methylindole is used in the preparation of indolylindazoles and indolylpyrazolopyridines, which are studied for their activity as interleukin-2 inducible T cell kinase inhibitors.
Anti-HIV Agent Research
It functions as a reactant in the synthesis of arylsulfonylacetylindoles, investigated for their potential as anti-HIV-1 agents.
| Molecular weight | 131.17 |
|---|---|
| Empirical formula | C9H9N |
| Assay | 97% |
| Boiling point | 112 °C/5 mmHg(lit.) |
| Density | 1.059 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.607(lit.) |
| Application | • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators• Reactant for preparation of indole linked triazole derivatives as antifungal agents• Reactant for preparation of N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for management of hyperglycemia in diabetes• Reactant for preparation of aminoguanidine derivatives of arylsulfonylacylindoles as antifungal agents• Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors• Reactant for preparation of arylsulfonylacetylindoles as anti-HIV-1 agents |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Methylindole primarily used for?
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6-Methylindole is a versatile building block used in chemical synthesis, particularly for developing potential anticancer, antifungal, anti-HIV agents, and treatments for diabetes.
What are the CAS number and chemical formula for 6-Methylindole?
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The CAS number is 3420-02-8, and the chemical formula is C9H9N.
What grade and purity does Tech Serve Solutions supply for 6-Methylindole?
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Tech Serve Solutions supplies 6-Methylindole with an assay of 97%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 6-Methylindole be handled safely?
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6-Methylindole is a warning substance (GHS07) that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handling requires a dust mask (type N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is 6-Methylindole a controlled substance?
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The provided data does not indicate that 6-Methylindole is a controlled substance.
How is 6-Methylindole packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details for 6-Methylindole will be provided upon inquiry.
How can I request a quote or sample of 6-Methylindole?
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To request a quote or sample of 6-Methylindole, please contact our sales team through the website or designated inquiry channels.
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