Sebacic acid bis(N-succinimidyl) ester
Sebacic acid bis(N-succinimidyl) ester (CAS: 23024-29-5, Formula: C18H24N2O8) is a homobifunctional cross-linking reagent. With a molecular weight of 396.39 g/mol, it is primarily employed in chemical biology and synthesis. Its structure allows for the formation of stable amide bonds with primary amines, facilitating the conjugation of molecules and modification of proteins in research and development settings. It is ideal for applications requiring precise molecular spacing.
- IUPAC
- DSSeb,Di(N-succinimidyl) sebacate
- Synonyms
- Di(N-succinimidyl) sebacateDSSeb
Protein Cross-linking
This reagent is used to covalently link proteins, enabling the study of protein-protein interactions and the stabilisation of protein complexes. The sebacate spacer provides a defined distance between conjugated molecules.
Bioconjugation
Sebacic acid bis(N-succinimidyl) ester can be utilised to conjugate biomolecules such as peptides, antibodies, or nucleic acids to surfaces or other molecules. This is essential for developing diagnostic assays and targeted drug delivery systems.
Surface Modification
It enables the functionalisation of surfaces with amine-reactive groups. This is valuable in the development of biosensors, chromatography media, and biomaterials with specific surface properties.
Chemical Synthesis
As a versatile building block, it participates in various organic synthesis pathways, particularly those involving the creation of polymeric structures or complex molecular architectures via amide bond formation.
| Molecular weight | 396.39 |
|---|---|
| Empirical formula | C18H24N2O8 |
| Assay | ≥97.0% (CHN)≥97.0% |
| Storage temperature | −20°C |
| Melting point | 162-167 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sebacic acid bis(N-succinimidyl) ester used for?
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Sebacic acid bis(N-succinimidyl) ester is primarily used as a homobifunctional cross-linking reagent in chemical biology and synthesis for applications such as protein cross-linking, bioconjugation, and surface modification.
What is the CAS number and formula for Sebacic acid bis(N-succinimidyl) ester?
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The CAS number is 23024-29-5 and the molecular formula is C18H24N2O8.
What grade and purity does Tech Serve Solutions supply for Sebacic acid bis(N-succinimidyl) ester?
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Tech Serve Solutions supplies Sebacic acid bis(N-succinimidyl) ester with an assay of ≥97.0%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling Sebacic acid bis(N-succinimidyl) ester?
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This compound is a Warning substance (GHS07) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves should be worn. Handle in a well-ventilated area.
How is Sebacic acid bis(N-succinimidyl) ester packed, shipped, and exported?
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Sebacic acid bis(N-succinimidyl) ester is typically stored at -20°C. Packing and shipping are conducted according to international regulations for chemical substances. TSS is a global supplier and exporter.
How can I request a quote or sample for Sebacic acid bis(N-succinimidyl) ester?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or by phone, referencing product code 23024-29-5.
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