6α-Hydroxycortisol
6α-Hydroxycortisol (CAS: 2242-98-0), with the molecular formula C21H30O6 and a molecular weight of 378.46 g/mol, is a significant corticosteroid derivative. This compound plays a role in the study of steroid hormone metabolism and cellular signaling pathways. It is primarily utilized in biochemical research and as a reference standard for analytical purposes, contributing to a deeper understanding of endocrine system functions and related biological processes.
- IUPAC
- 4-Pregnene-6α,11β,17,21-tetrol-3,20-dione

Biochemical Research
6α-Hydroxycortisol serves as a valuable tool in biochemical research, aiding investigations into steroid hormone metabolism and the mechanisms of corticosteroid action within cellular systems.
Cell Signaling Studies
This compound is employed in studies focused on cell signaling pathways, particularly those involving hormones and their downstream effects on cellular behaviour and gene expression.
Analytical Reference Standard
Due to its defined chemical properties, 6α-Hydroxycortisol is used as a reference standard in analytical chemistry for the identification and quantification of related compounds in complex biological matrices.
| Molecular weight | 378.46 |
|---|---|
| Empirical formula | C21H30O6 |
| Assay | ≥98% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6α-Hydroxycortisol used for?
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6α-Hydroxycortisol is used in biochemical research, studies on cell signaling pathways, and as an analytical reference standard for related compounds.
What are the CAS number and formula for 6α-Hydroxycortisol?
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The CAS number for 6α-Hydroxycortisol is 2242-98-0, and its molecular formula is C21H30O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6α-Hydroxycortisol with an assay of ≥98%. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations when handling 6α-Hydroxycortisol?
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Handling 6α-Hydroxycortisol requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is 6α-Hydroxycortisol packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions expertly packs, ships, and exports chemicals like 6α-Hydroxycortisol, adhering to all necessary international regulations for safe transit.
How can I request a quote or sample for 6α-Hydroxycortisol?
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To request a quote or sample for 6α-Hydroxycortisol, please contact the Tech Serve Solutions sales team via our website or listed contact details.
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