6α-Hydroxyestradiol
6α-Hydroxyestradiol (CAS: 1229-24-9), with the molecular formula C18H24O3 and a molecular weight of 288.38 g/mol, is a steroid hormone. As a hydroxylated derivative of estradiol, it plays a role in biological pathways. This compound is primarily utilized in scientific research, particularly within cell biology, cell signaling, and neuroscience studies. Its precise biological functions and applications are subjects of ongoing scientific investigation.
- IUPAC
- 1,3,5(10)-Estratriene-3,6α,17β-triol
- Synonyms
- 1,3,5(10)-Estratriene-3,6α,17β-triol

Biochemical Research
6α-Hydroxyestradiol is used as a research chemical in studies investigating steroid hormone metabolism and action. It aids in understanding the specific roles of hydroxylated estrogens in various biological processes.
Cell Signaling Studies
This compound is valuable for researchers exploring estrogen receptor interactions and downstream signaling pathways. It helps elucidate the nuanced effects of different estrogen metabolites on cellular functions.
Neuroscience Research
In neuroscience, 6α-Hydroxyestradiol may be employed to study the influence of estrogens on neuronal function and development. Its role in modulating neural pathways is an area of scientific interest.
Endocrinology Research
It serves as a tool in endocrinological research to investigate the biosynthesis, metabolism, and biological activity of steroid hormones. This aids in a deeper understanding of endocrine system regulation.
| Molecular weight | 288.38 |
|---|---|
| Empirical formula | C18H24O3 |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-40 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6α-Hydroxyestradiol used for?
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6α-Hydroxyestradiol is primarily used as a research chemical in fields such as cell biology, cell signaling, neuroscience, and endocrinology to study steroid hormone metabolism and action.
What is the CAS number and formula for 6α-Hydroxyestradiol?
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The CAS number for 6α-Hydroxyestradiol is 1229-24-9 and its empirical formula is C18H24O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6α-Hydroxyestradiol as a research-grade chemical. The specific assay and purity details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 6α-Hydroxyestradiol be handled?
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Handle 6α-Hydroxyestradiol with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation or use a respirator. Avoid inhalation of dust or vapours. Refer to the Safety Data Sheet for detailed handling instructions due to hazards H302, H312, H315, H319, H332, H335, and H351.
Is 6α-Hydroxyestradiol a controlled substance?
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The provided data does not indicate that 6α-Hydroxyestradiol is a controlled substance. However, users should verify any relevant local regulations.
How is 6α-Hydroxyestradiol packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports 6α-Hydroxyestradiol in compliance with all relevant international regulations for chemical transport. Packaging is designed to maintain product integrity and safety.
How can I request a sample or quote for 6α-Hydroxyestradiol?
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To request a sample or quote for 6α-Hydroxyestradiol, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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