6-Bromohexanoyl chloride
6-Bromohexanoyl chloride (CAS 22809-37-6) is a reactive acyl halide with the linear formula Br(CH <sub>2</sub>)<sub>5</sub>COCl and a molar mass of 213.50 g/mol. It serves as a valuable building block in organic synthesis, primarily used for introducing the 6-bromohexanoyl moiety into various molecular structures. Its applications are centred around the preparation of specialised organic compounds, making it a key reagent for researchers and chemists in synthetic and medicinal chemistry.
- IUPAC
- 6-Bromocaproyl chloride,6-Bromohexanoic acid chloride
- Synonyms
- 6-Bromocaproyl chloride6-Bromohexanoic acid chloride
Synthesis of Chiral Amides
6-Bromohexanoyl chloride is employed in the synthesis of chiral intermediates, such as (S)- or (R)-N-(6-bromohexanoyl)-α-methylbenzylamine. This reaction type is crucial for building complex stereospecific molecules.
Preparation of Ketone Derivatives
It is used in reactions to prepare functionalised ketones, including compounds like 1-bromoheptadecan-6-one and 1-bromooctadecan-6-one, which can serve as precursors in further synthetic pathways.
Organic Synthesis Building Block
As a difunctional molecule, it allows for selective reactions at either the acyl chloride or the alkyl bromide terminus, facilitating the construction of diverse organic frameworks.
| Molecular weight | 213.50 |
|---|---|
| Linear formula | Br(CH2)5COCl |
| Assay | 97% |
| Boiling point | 130 °C/20 mmHg(lit.) |
| Density | 1.395 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.486(lit.) |
| Application | 6-Bromohexanoyl chloride has been used in preparation of:• (S)- or (R)-N-(6-bromohexanoyl)-α-methylbenzylamine1• 1-bromoheptadecan-6-one and 1-bromooctadecan-6-one2 |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34-36/37 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Bromohexanoyl chloride used for?
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6-Bromohexanoyl chloride is primarily used as a building block in organic synthesis for the preparation of specialised organic compounds, including chiral amides and functionalised ketones.
What is the CAS number and formula for 6-Bromohexanoyl chloride?
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The CAS number for 6-Bromohexanoyl chloride is 22809-37-6, and its linear formula is Br(CH <sub>2</sub>)<sub>5</sub>COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Bromohexanoyl chloride with a minimum assay of 97%. This product is intended for laboratory and research purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 6-Bromohexanoyl chloride be handled?
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6-Bromohexanoyl chloride is a corrosive substance that reacts violently with water. Handle with extreme care using appropriate personal protective equipment, including face shields, chemical-resistant gloves, and respirators, in a well-ventilated area. Avoid contact with water and moisture.
Does TSS export 6-Bromohexanoyl chloride?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 6-Bromohexanoyl chloride, to researchers and industries worldwide.
How can I request a quote or sample?
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To request a quote or sample of 6-Bromohexanoyl chloride, please contact our sales department through the website or by phone, providing your specific requirements.
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