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6-(Boc-amino)hexyl bromide

CAS 142356-33-0C11H22BrNO2Chemical Synthesis

6-(Boc-amino)hexyl bromide (CAS: 142356-33-0) is an organic compound with the empirical formula C11H22BrNO2 and a molecular weight of 280.20 g/mol. This protected amine features a tert-butoxycarbonyl (Boc) group and a terminal bromide, making it a valuable bifunctional linker. It is primarily utilised as a building block in organic synthesis, particularly for introducing hexyl chains with a protected amine functionality in the preparation of complex molecules and pharmaceutical intermediates.

IUPAC
tert-Butyl N-(6-bromohexyl)carbamate
Synonyms
tert-Butyl N-(6-bromohexyl)carbamate
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6-(Boc-amino)hexyl bromide (C11H22BrNO2) — chemical structure, CAS 142356-33-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Bifunctional LinkersBuilding BlocksChemical BiologyChemical SynthesisLinkers and CrosslinkersNitrogen CompoundsOrganic Building BlocksProtected Amines More...
01 /Applications

Organic Synthesis Building Block

This compound serves as a versatile building block in organic synthesis. The bromide moiety allows for nucleophilic substitution reactions, while the Boc-protected amine can be deprotected under acidic conditions for further functionalization.

Linker Chemistry

Its bifunctional nature makes it suitable for use as a linker in various chemical applications, enabling the connection of different molecular entities or surfaces.

Pharmaceutical Intermediate Synthesis

It finds application in the synthesis of pharmaceutical intermediates, where precise control over amine protection and chain extension is required.

Chemical Biology Research

Used in chemical biology to construct novel molecules for probing biological systems or developing targeted therapeutics, leveraging its specific structural features.

02 /Properties
Molecular weight280.20
Empirical formulaC11H22BrNO2
Assay≥97.0% (GC)
Density1.192 g/mL at 20 °C(lit.)
Refractive indexn20/D 1.473
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H318Causes serious eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Transport (UN / ADR)UN 3082 9 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi,N
Risk statements (R)41-52/53
Safety statements (S)61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
142356-33-0
MDL number
MFCD06201019
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 6-(Boc-amino)hexyl bromide used for?

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6-(Boc-amino)hexyl bromide is primarily used as a building block in organic synthesis and linker chemistry, particularly in the pharmaceutical and chemical biology fields. It allows for the introduction of a protected amine via a hexyl chain.

What are the CAS number and formula for 6-(Boc-amino)hexyl bromide?

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The CAS number for 6-(Boc-amino)hexyl bromide is 142356-33-0, and its empirical formula is C11H22BrNO2.

What grade and purity does Tech Serve Solutions supply for 6-(Boc-amino)hexyl bromide?

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Tech Serve Solutions supplies 6-(Boc-amino)hexyl bromide with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 6-(Boc-amino)hexyl bromide be handled safely?

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6-(Boc-amino)hexyl bromide is classified as Danger (GHS05) and can cause serious eye damage (H318). Appropriate personal protective equipment, including eyeshields and suitable gloves, should be worn. Ensure adequate ventilation and avoid contact with eyes.

How is 6-(Boc-amino)hexyl bromide packed and shipped?

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6-(Boc-amino)hexyl bromide is packed and shipped in accordance with international regulations for hazardous materials. It is classified as UN 3082, 9, PGIII.

How can I request a sample or quote for 6-(Boc-amino)hexyl bromide?

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To request a sample or quote for 6-(Boc-amino)hexyl bromide, please contact our sales team via the website or email, specifying the product CAS number and desired quantity.

Need 6-(Boc-amino)hexyl bromide in a specific grade or volume?