6-(Boc-amino)hexyl bromide
6-(Boc-amino)hexyl bromide (CAS: 142356-33-0) is an organic compound with the empirical formula C11H22BrNO2 and a molecular weight of 280.20 g/mol. This protected amine features a tert-butoxycarbonyl (Boc) group and a terminal bromide, making it a valuable bifunctional linker. It is primarily utilised as a building block in organic synthesis, particularly for introducing hexyl chains with a protected amine functionality in the preparation of complex molecules and pharmaceutical intermediates.
- IUPAC
- tert-Butyl N-(6-bromohexyl)carbamate
- Synonyms
- tert-Butyl N-(6-bromohexyl)carbamate

Organic Synthesis Building Block
This compound serves as a versatile building block in organic synthesis. The bromide moiety allows for nucleophilic substitution reactions, while the Boc-protected amine can be deprotected under acidic conditions for further functionalization.
Linker Chemistry
Its bifunctional nature makes it suitable for use as a linker in various chemical applications, enabling the connection of different molecular entities or surfaces.
Pharmaceutical Intermediate Synthesis
It finds application in the synthesis of pharmaceutical intermediates, where precise control over amine protection and chain extension is required.
Chemical Biology Research
Used in chemical biology to construct novel molecules for probing biological systems or developing targeted therapeutics, leveraging its specific structural features.
| Molecular weight | 280.20 |
|---|---|
| Empirical formula | C11H22BrNO2 |
| Assay | ≥97.0% (GC) |
| Density | 1.192 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.473 |

Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 41-52/53 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(Boc-amino)hexyl bromide used for?
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6-(Boc-amino)hexyl bromide is primarily used as a building block in organic synthesis and linker chemistry, particularly in the pharmaceutical and chemical biology fields. It allows for the introduction of a protected amine via a hexyl chain.
What are the CAS number and formula for 6-(Boc-amino)hexyl bromide?
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The CAS number for 6-(Boc-amino)hexyl bromide is 142356-33-0, and its empirical formula is C11H22BrNO2.
What grade and purity does Tech Serve Solutions supply for 6-(Boc-amino)hexyl bromide?
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Tech Serve Solutions supplies 6-(Boc-amino)hexyl bromide with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 6-(Boc-amino)hexyl bromide be handled safely?
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6-(Boc-amino)hexyl bromide is classified as Danger (GHS05) and can cause serious eye damage (H318). Appropriate personal protective equipment, including eyeshields and suitable gloves, should be worn. Ensure adequate ventilation and avoid contact with eyes.
How is 6-(Boc-amino)hexyl bromide packed and shipped?
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6-(Boc-amino)hexyl bromide is packed and shipped in accordance with international regulations for hazardous materials. It is classified as UN 3082, 9, PGIII.
How can I request a sample or quote for 6-(Boc-amino)hexyl bromide?
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To request a sample or quote for 6-(Boc-amino)hexyl bromide, please contact our sales team via the website or email, specifying the product CAS number and desired quantity.
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