5-(Trifluoromethyl)-1,3-phenylenediamine
5-(Trifluoromethyl)-1,3-phenylenediamine (CAS 368-53-6) is an organic building block for chemical synthesis. This fluorinated aromatic compound, also known as CF3C6H3(NH2)2, is a key intermediate in the development of advanced materials, including hybrid polymers and fluorinated polyimides. Its structure, featuring a trifluoromethyl group and two amine functionalities on a phenyl ring, makes it valuable for creating materials with unique thermal and chemical properties. Available from TSS, it meets rigorous quality standards for research and industrial applications.
- Synonyms
- CF3C6H3(NH2)2

Synthesis of Hybrid Materials
Utilized in the creation of hybrid materials incorporating novel polyhedral oligomeric silsesquioxane structures, enhancing material properties.
Fluorinated Aromatic Polyimides
Serves as a crucial component in the synthesis of fluorinated aromatic polyimide films, contributing to their thermal stability and chemical resistance.
Organic Synthesis Intermediate
A versatile building block for constructing complex organic molecules in research and development settings.
| Molecular weight | 176.14 |
|---|---|
| Linear formula | CF3C6H3(NH2)2 |
| Assay | 98% |
| Application | 5-(Trifluoromethyl)-1,3-phenylenediamine was used in the synthesis of:• hybrid materials based on new polyhedral oligomeric silsesquioxane1• fluorinated aromatic polyimide films2 |
| Melting point | 87-89 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(Trifluoromethyl)-1,3-phenylenediamine used for?
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This compound is primarily used as a building block in organic synthesis, particularly for creating hybrid materials and fluorinated aromatic polyimide films.
What is the CAS number and formula for 5-(Trifluoromethyl)-1,3-phenylenediamine?
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The CAS number is 368-53-6, and its linear formula is CF3C6H3(NH2)2.
What is the grade and purity of this chemical?
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This chemical is supplied at an assay of 98%.
What are the primary hazards associated with 5-(Trifluoromethyl)-1,3-phenylenediamine?
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This compound is classified under GHS05 and GHS07 with the signal word 'Danger'. It is harmful if swallowed (H302) and causes serious eye damage (H318).
How is 5-(Trifluoromethyl)-1,3-phenylenediamine typically shipped?
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As a specialist global supplier and exporter, TSS adheres to all relevant regulations for packing and shipping chemical products like 5-(Trifluoromethyl)-1,3-phenylenediamine.
How can I request a quote for 5-(Trifluoromethyl)-1,3-phenylenediamine?
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To request a quote, please contact our sales department via the website or by telephone, providing the product name and CAS number (368-53-6).
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