1-Chloro-N,N,2-trimethyl-1-propenylamine
1-Chloro-N,N,2-trimethyl-1-propenylamine (CAS 26189-59-3), a halogenated hydrocarbon, is a versatile organic building block. With a molecular weight of 133.62 g/mol, it serves as a key reagent in organic synthesis. Its primary application is the efficient conversion of carboxylic acids into their corresponding acid chlorides under neutral conditions, a critical transformation in various chemical manufacturing processes.
- IUPAC
- Ghosez′s reagent
- Synonyms
- 26189-59-3, (CH3)2C=C(Cl)N(CH3)2

Acid Chloride Synthesis
1-Chloro-N,N,2-trimethyl-1-propenylamine facilitates the conversion of carboxylic acids to acid chlorides. This reaction proceeds under neutral conditions, minimizing side reactions and preserving sensitive functional groups.
Organic Synthesis Intermediate
As a reactive halogenated hydrocarbon, this compound acts as a valuable intermediate in complex organic syntheses. It is employed in the construction of more elaborate molecular structures for research and development.
Reagent for Functional Group Transformation
It is utilised to introduce specific functionalities into organic molecules. Its reactivity allows for selective transformations, making it useful in multi-step synthetic pathways.
| Molecular weight | 133.62 |
|---|---|
| Linear formula | (CH3)2C=C(Cl)N(CH3)2 |
| Assay | 96% |
| Boiling point | 129-130 °C(lit.) |
| Density | 1.01 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.453(lit.) |
| Storage temperature | 2-8°C |
| Application | Conversion of carboxylic acids to acid chlorides under neutral reaction conditions |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 26 °C / 78.8 °F |
| Transport (UN / ADR) | UN 2734 8/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Chloro-N,N,2-trimethyl-1-propenylamine used for?
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This compound is primarily used for the conversion of carboxylic acids to acid chlorides under neutral reaction conditions. It also serves as a general building block and intermediate in organic synthesis.
What is the CAS number and formula for 1-Chloro-N,N,2-trimethyl-1-propenylamine?
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The CAS number is 26189-59-3. The linear formula is (CH3)2C=C(Cl)N(CH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Chloro-N,N,2-trimethyl-1-propenylamine with an assay of 96%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 1-Chloro-N,N,2-trimethyl-1-propenylamine be handled safely?
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This compound is classified as dangerous. It is flammable and causes severe skin burns and eye damage. Handle with extreme care, using full-face protection, chemical-resistant gloves, and appropriate respiratory protection in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling procedures.
Is 1-Chloro-N,N,2-trimethyl-1-propenylamine a controlled substance?
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The provided data does not indicate that 1-Chloro-N,N,2-trimethyl-1-propenylamine is a controlled substance.
How is 1-Chloro-N,N,2-trimethyl-1-propenylamine packed and exported?
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Products are packed and exported in compliance with all relevant national and international regulations for hazardous materials. Specific packaging details depend on quantity and destination, ensuring safe transport.
How can I request a sample or quote for 1-Chloro-N,N,2-trimethyl-1-propenylamine?
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To request a sample or a quote, please contact our sales department via the website or by telephone, providing your specific requirements.
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