5-Nitro-2-furoyl chloride
5-Nitro-2-furoyl chloride (CAS 25084-14-4), with the molecular formula C5H2ClNO4 and a molecular weight of 175.53, is a furan derivative utilised as a building block in chemical synthesis. This heterocyclic compound serves as a valuable intermediate for introducing the 5-nitro-2-furoyl moiety into more complex molecular structures. Its reactivity makes it suitable for various organic transformations, particularly in the development of novel chemical entities.

Organic Synthesis Intermediate
5-Nitro-2-furoyl chloride is employed as a reactive intermediate in the synthesis of diverse organic compounds. Its acyl chloride functionality readily participates in reactions such as acylation, enabling the formation of esters, amides, and other derivatives.
Heterocyclic Chemistry
As a furan derivative, this compound is instrumental in heterocyclic chemistry research and development. It can be used to construct or modify furan-containing ring systems, which are prevalent in pharmaceuticals and other fine chemicals.
Building Block for Novel Molecules
The presence of both a nitro group and an acyl chloride on the furan ring provides specific reactivity, making 5-Nitro-2-furoyl chloride a useful building block for creating novel molecules with targeted properties.
| Molecular weight | 175.53 |
|---|---|
| Empirical formula | C5H2ClNO4 |
| Assay | 95% |
| Melting point | 34-41 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Nitro-2-furoyl chloride used for?
+
5-Nitro-2-furoyl chloride is primarily used as a building block and intermediate in organic synthesis and heterocyclic chemistry for creating more complex molecular structures.
What is the CAS number and chemical formula for 5-Nitro-2-furoyl chloride?
+
The CAS number is 25084-14-4 and the empirical formula (Hill notation) is C5H2ClNO4.
What grade and purity does Tech Serve Solutions supply for 5-Nitro-2-furoyl chloride?
+
Tech Serve Solutions supplies 5-Nitro-2-furoyl chloride with an assay of 95%. This is a technical grade material and is not represented as USP, BP, or EP.
How should 5-Nitro-2-furoyl chloride be handled?
+
5-Nitro-2-furoyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (type N100 or P3 filters), is essential. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
How is 5-Nitro-2-furoyl chloride packed, shipped, and exported?
+
5-Nitro-2-furoyl chloride is classified under UN 3261, Packing Group II, for transport. It is carefully packed according to international regulations for hazardous materials and exported globally by Tech Serve Solutions.
How can I request a quote or sample for 5-Nitro-2-furoyl chloride?
+
To request a quote or sample, please contact our sales department with your specific requirements, referencing the product name and CAS number 25084-14-4.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis