5-Methyl-2-thiouridine
5-Methyl-2-thiouridine (CAS: 32738-09-3), with the molecular formula C10H14N2O5S and a molecular weight of 274.29 g/mol, is a modified nucleobase found in the tRNA of certain thermophilic organisms. It is utilised in scientific research to investigate the physical and chemical characteristics that contribute to the high stability of tRNA and other nucleic acid structures. TSS supplies this compound for research and laboratory applications.
- IUPAC
- m5s2U

Nucleic Acid Research
Used to study the stability conferred by modified nucleobases in tRNA and other nucleic acid structures.
Biochemical Studies
Employed in research to understand the unique properties of modified nucleotides, particularly in extremophilic organisms.
Biophysical Investigations
Facilitates research into the structural and functional aspects of nucleic acids, contributing to the understanding of molecular stability.
| Molecular weight | 274.29 |
|---|---|
| Empirical formula | C10H14N2O5S |
| Storage temperature | −20°C |
| Application | 5-Methyl-2-thiouridine (m5s2U) is a modified base found in the tRNA of certain extreme thermophiles. 5-Methyl-2-thiouridine may be used to study the physical chemical properties that confer high stability to tRNA and other nucleic acid structures. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methyl-2-thiouridine used for?
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5-Methyl-2-thiouridine is used in research to study the physical and chemical properties that provide high stability to tRNA and other nucleic acid structures, particularly in extremophilic organisms.
What are the CAS number and formula for 5-Methyl-2-thiouridine?
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The CAS number is 32738-09-3 and the empirical formula is C10H14N2O5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methyl-2-thiouridine for research purposes. The specific assay and grade are available on the product's Certificate of Analysis. This product is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 5-Methyl-2-thiouridine be handled and stored?
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5-Methyl-2-thiouridine should be stored at -20°C. As per WGK Germany 3, appropriate safety precautions should be taken during handling to minimise exposure. Consult the Safety Data Sheet for detailed handling information.
Is 5-Methyl-2-thiouridine a controlled substance?
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The provided data does not indicate that 5-Methyl-2-thiouridine is a controlled substance.
How is 5-Methyl-2-thiouridine packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals according to international regulations. Specific packaging details can be provided upon request for your order.
How can I request a sample or quote for 5-Methyl-2-thiouridine?
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To request a sample or a quotation for 5-Methyl-2-thiouridine, please contact our sales department through the TSS website or by phone, providing your details and the product CAS number 32738-09-3.
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