5-Maleimido-eosin
5-Maleimido-eosin (CAS 150322-02-4), with the empirical formula C24H9Br4NO7 and a molecular weight of 742.95 g/mol, is a vital fluorescent probe. It is primarily utilised in biochemical research for detecting hereditary spherocytosis (HS) through its binding affinity. This compound is supplied by Tech Serve Solutions for fluorescence applications, offering researchers a reliable tool for specific diagnostic assays.
- IUPAC
- Eosin-5-maleimide

Hereditary Spherocytosis Detection
5-Maleimido-eosin (EMA) binding is a widely employed method in flow cytometry for the diagnosis of hereditary spherocytosis (HS). This application leverages the compound's ability to bind specifically, aiding in the identification of red blood cell abnormalities characteristic of HS.
Fluorescent Labeling and Probing
As a fluorescent label, 5-Maleimido-eosin is valuable for various biological studies. Its fluorescent properties make it suitable for applications in detecting and visualising cellular components and processes, particularly in membrane research.
Biochemical Assays
This compound serves as a reagent in biochemical assays, particularly where a fluorescent indicator with specific binding capabilities is required. Its reactive maleimide group allows for conjugation to biomolecules.
| Molecular weight | 742.95 |
|---|---|
| Empirical formula | C24H9Br4NO7 |
| Assay | ≥93% (HPLC) |
| Grade | for fluorescence |
| Storage temperature | 2-8°C |
| Application | 5-Maleimido-eosin (eosin-5-maleimide, EMA) binding is widely used in a flow cytometry to detect hereditary spherocytosis (HS). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 524 nm; λem 545 nm (after derivatization with 2-mercaptoethanol) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Maleimido-eosin used for?
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5-Maleimido-eosin (EMA) is primarily used in flow cytometry for the detection of hereditary spherocytosis (HS). It also functions as a fluorescent label and probe in various biochemical and membrane research applications.
What is the CAS number and formula for 5-Maleimido-eosin?
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The CAS number for 5-Maleimido-eosin is 150322-02-4, and its empirical formula is C24H9Br4NO7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Maleimido-eosin for fluorescence applications with an assay of ≥93% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 5-Maleimido-eosin be handled and stored?
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Handle 5-Maleimido-eosin with appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter. Store the chemical at 2-8°C.
Is 5-Maleimido-eosin a controlled substance?
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The provided safety data does not indicate that 5-Maleimido-eosin is a controlled substance.
How are products like 5-Maleimido-eosin packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and adherence to shipping regulations for safe and compliant delivery worldwide.
How can I request a sample or quote for 5-Maleimido-eosin?
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To request a sample or obtain a quote for 5-Maleimido-eosin, please contact our sales team through the details provided on our website.
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