5-Iodo-2′-deoxycytidine
5-Iodo-2′-deoxycytidine (CAS: 611-53-0, Formula: C9H12IN3O4, MW: 353.11) is a modified nucleoside analog. This biochemical reagent is primarily employed in constructing DNA oligomers for structural investigations and photoactivated cross-linking. It also serves as a key intermediate in the synthesis of other complex modified nucleosides, finding utility in advanced biochemical research and material science applications.
- IUPAC
- 5-Iododeoxycytidine

DNA Oligomer Construction
Utilised in building specific DNA sequences for structural studies and photoactivated cross-linking experiments. This allows for detailed analysis of DNA architecture and function.
Synthesis of Modified Nucleosides
Serves as a precursor for synthesising other specialised nucleoside derivatives. Examples include its use in creating compounds for semiconductor electrodes and complex heterocyclic structures.
Biochemical Research Reagent
A valuable tool for researchers in molecular biology, biochemistry, and related fields. Enables investigations into DNA modification and analogue development.
| Molecular weight | 353.11 |
|---|---|
| Empirical formula | C9H12IN3O4 |
| Assay | ≥99% (HPLC) |
| Storage temperature | −20°C |
| Application | 5-Iodo-2′-deoxycytidine (5-iododeoxycytidine) is used in the construction of DNA oligomers to enable structural studies and photoactivated cross-linking. 5-Iodo-2′-deoxycytidine is used in the synthesis of other modified nucleosides, such as 5-ethynylferrocenyl-2′-deoxycytidine used in semiconductor electrodes and 10-(2-deoxyβ-D-ribofuranosyl)pyrimido[4′,5′:4,5]pyrimido[1,6-a]indole-6,9(7H)-dione (dCPPI). |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Iodo-2′-deoxycytidine used for?
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5-Iodo-2′-deoxycytidine is used in the construction of DNA oligomers for structural studies and photoactivated cross-linking, and in the synthesis of other modified nucleosides.
What is the CAS number and formula for 5-Iodo-2′-deoxycytidine?
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The CAS number is 611-53-0 and the molecular formula is C9H12IN3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Iodo-2′-deoxycytidine with a purity of ≥99% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.
How should 5-Iodo-2′-deoxycytidine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. It is classified as harmful if swallowed (H302).
How is 5-Iodo-2′-deoxycytidine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is typically stored at −20°C and shipped according to standard chemical logistics protocols.
How can I request a sample or quote for 5-Iodo-2′-deoxycytidine?
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Please contact our sales team through the TSS website to request a sample or a formal quotation for 5-Iodo-2′-deoxycytidine.
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