5-Methoxypsoralen
5-Methoxypsoralen (CAS: 484-20-8, C12H8O4, MW: 216.19) is a furanocoumarin derived from plants like Citrus aurantium. This compound is primarily recognised for its role in phototherapy and as a research chemical in fields such as cancer research and cell biology. Its photochemical properties also lend themselves to applications in materials science, particularly in the development of light-emitting dopants and fluorescent dyes.
- IUPAC
- 4-Methoxyfuro[3,2-g]benzopyrane-7-one,Bergapten
- Synonyms
- Bergapten4-Methoxyfuro[3,2-g]benzopyrane-7-one

Phototherapy and Dermatology
5-Methoxypsoralen, often in combination with UVA radiation (PUVA therapy), has been historically used in dermatological treatments for certain skin conditions. Its photosensitising properties are key to this application.
Cancer Research
As an agent with potential antitumor activity, 5-Methoxypsoralen is utilised in preclinical research to investigate mechanisms of cancer cell growth and to explore novel therapeutic strategies. Its effects on cellular processes are a focus of study.
Materials Science
The compound's photoluminescent and fluorescent characteristics make it a subject of interest in materials science for the development of optical and electronic devices. It can be explored as a dopant or dye component.
Phytochemical Research
Found naturally in certain plants, 5-Methoxypsoralen is studied as a significant phytochemical. Research involves its isolation, characterisation, and understanding of its biological activities within a plant context.
| Molecular weight | 216.19 |
|---|---|
| Empirical formula | C12H8O4 |
| Assay | 99% |
| Melting point | 190-193 °C(lit.) |

Hazard statements
- H334May cause allergy or asthma symptoms if inhaled
- H340May cause genetic defects
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-43 |
| Safety statements (S) | 53-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methoxypsoralen used for?
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5-Methoxypsoralen is used in phototherapy, cancer research, cell biology studies, and as a component in materials science for applications like fluorescent dyes and dopants. It is also studied as a phytochemical.
What is the CAS number and formula for 5-Methoxypsoralen?
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The CAS number is 484-20-8 and the empirical formula is C12H8O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methoxypsoralen with an assay of 99%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 5-Methoxypsoralen be handled safely?
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Due to its potential to cause genetic defects (H340) and cancer (H350), and its risk of causing allergy or asthma symptoms if inhaled (H334), handle with extreme caution. Use safety equipment including eyeshields, face shields, gloves, and a P2 respirator. Ensure good ventilation and avoid exposure.
Is 5-Methoxypsoralen a controlled substance?
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The provided data does not indicate that 5-Methoxypsoralen is a controlled substance.
How is 5-Methoxypsoralen packed, shipped, and exported?
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Tech Serve Solutions handles the packing, shipping, and export of 5-Methoxypsoralen in accordance with all relevant regulations, ensuring safe and compliant delivery to global destinations.
How can I request a sample or quote for 5-Methoxypsoralen?
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To request a sample or a quote for 5-Methoxypsoralen, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.
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