2-Hydroxy-3-methylbutyric acid
2-Hydroxy-3-methylbutyric acid (CAS 4026-18-0) is a chiral carboxylic acid with the linear formula (CH3)2CHCH(OH)CO2H and a molecular weight of 118.13 g/mol. This organic building block is characterised by its hydroxyl and carboxyl functional groups, making it suitable for various chemical synthesis applications. It has been notably employed as an internal standard in analytical chemistry, specifically for the determination of substances like ethylene glycol and gamma-hydroxybutyrate in biological samples.
- IUPAC
- 2-Hydroxyisovaleric acid
- Synonyms
- 2-Hydroxyisovaleric acid
Analytical Standard
Utilised as an internal standard for the precise analysis of compounds such as ethylene glycol and gamma-hydroxybutyrate (GHB) in complex matrices like whole blood, ensuring accurate quantification.
Organic Synthesis
Serves as a versatile building block in organic synthesis, owing to its dual hydroxyl and carboxylic acid functionalities, enabling the construction of more complex molecules.
Research Reagent
Employed in research laboratories for exploring novel synthetic pathways and for developing new chemical entities or processes.
| Molecular weight | 118.13 |
|---|---|
| Linear formula | (CH3)2CHCH(OH)CO2H |
| Assay | 99% |
| Application | 2-Hydroxy-3-methylbutyric acid was employed as internal standard for analysis of ethylene glycol (EG) and γ-hydroxybutyrate (GHB) in whole blood1. |
| Melting point | 86-87 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxy-3-methylbutyric acid used for?
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2-Hydroxy-3-methylbutyric acid is primarily used as an internal standard in analytical chemistry for quantifying substances like ethylene glycol and gamma-hydroxybutyrate. It also serves as a building block in organic synthesis and as a research reagent.
What are the CAS number and chemical formula for 2-Hydroxy-3-methylbutyric acid?
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The CAS number for 2-Hydroxy-3-methylbutyric acid is 4026-18-0. Its linear formula is (CH3)2CHCH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Hydroxy-3-methylbutyric acid with a purity of 99%. This product is suitable for research and general laboratory use. TSS does not represent this product as USP, BP, or EP grade.
How should 2-Hydroxy-3-methylbutyric acid be handled safely?
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2-Hydroxy-3-methylbutyric acid is classified as a Warning substance. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Ensure good ventilation.
How is this chemical packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions offers 2-Hydroxy-3-methylbutyric acid for export. The product is carefully packed in accordance with international shipping regulations for hazardous materials. Please contact us for specific packaging and shipping details.
How can I request a sample or quote for 2-Hydroxy-3-methylbutyric acid?
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To request a sample or a quote for 2-Hydroxy-3-methylbutyric acid, please use the contact form on our website or call our sales department. Provide your details and the quantity required, and we will respond promptly.
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