5′-Chloro-2′-hydroxy-4′-methylacetophenone
5′-Chloro-2′-hydroxy-4′-methylacetophenone (CAS: 28480-70-8) is an organic compound with the linear formula ClC<sub>6</sub>H<sub>2</sub>(OH)(CH<sub>3</sub>)COCH<sub>3</sub> and a molecular weight of 184.62 g/mol. As a substituted acetophenone and a key building block, it is primarily utilised in chemical synthesis. This compound is a valuable intermediate for the preparation of more complex molecules within research and development settings.

Organic Synthesis Intermediate
5′-Chloro-2′-hydroxy-4′-methylacetophenone serves as a versatile intermediate in the synthesis of various organic compounds. Its functional groups allow for diverse chemical transformations, making it useful in constructing complex molecular architectures.
Research and Development
This compound is employed in laboratory settings for research purposes. It aids chemists in exploring new synthetic pathways and developing novel compounds with potential applications in different scientific fields.
Building Block for Complex Molecules
As a C9 building block, it is instrumental in the stepwise construction of larger molecules. Its specific substitution pattern offers a defined starting point for targeted synthetic strategies in medicinal chemistry and materials science.
| Molecular weight | 184.62 |
|---|---|
| Linear formula | ClC6H2(OH)(CH3)COCH3 |
| Assay | 98% |
| Melting point | 70-73 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5′-Chloro-2′-hydroxy-4′-methylacetophenone used for?
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5′-Chloro-2′-hydroxy-4′-methylacetophenone is primarily used as an intermediate in organic synthesis and as a building block in research and development for creating more complex molecules.
What is the CAS number and molecular formula for this compound?
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The CAS number is 28480-70-8, and the linear molecular formula is ClC<sub>6</sub>H<sub>2</sub>(OH)(CH<sub>3</sub>)COCH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5′-Chloro-2′-hydroxy-4′-methylacetophenone with an assay of 98%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
How should 5′-Chloro-2′-hydroxy-4′-methylacetophenone be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure adequate ventilation.
Is 5′-Chloro-2′-hydroxy-4′-methylacetophenone a controlled substance?
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The provided data does not indicate that 5′-Chloro-2′-hydroxy-4′-methylacetophenone is a controlled substance.
How is this chemical packed and exported?
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Tech Serve Solutions packs and exports chemicals according to international shipping regulations, ensuring safe and compliant transport globally.
How can I request a sample or a quote for 5′-Chloro-2′-hydroxy-4′-methylacetophenone?
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To request a sample or a quote, please contact our sales team through the website or by calling our office. Provide the product name and CAS number (28480-70-8) for prompt service.
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