5-Chloro-1,3-dimethoxybenzene
5-Chloro-1,3-dimethoxybenzene (CAS: 7051-16-3), with the linear formula ClC<sub>6</sub>H<sub>3</sub>(OCH<sub>3</sub>)<sub>2</sub> and a molecular weight of 172.61 g/mol, is a substituted aromatic ether. This organic compound serves as a valuable building block in chemical synthesis, particularly in the development of complex molecular structures. Its applications are found in research and development settings for creating novel compounds.
- Synonyms
- ClC6H3(OCH3)2
Organic Synthesis Intermediate
5-Chloro-1,3-dimethoxybenzene is utilised as a key intermediate in multi-step organic synthesis. Its reactive sites allow for further functionalisation in the construction of more complex molecules.
Pharmaceutical Research
This compound has been employed in the synthesis of potential pharmaceutical candidates. Notably, it was used in the regioselective synthesis of TMC-264, a tricyclic structure with a dibenzo[b,d]pyran-4,6-dione skeleton.
Building Block for Heterocycles
As a functionalised benzene derivative, it acts as a versatile building block for creating various heterocyclic compounds in academic and industrial research.
| Molecular weight | 172.61 |
|---|---|
| Linear formula | ClC6H3(OCH3)2 |
| Assay | 97% |
| Application | 5-Chloro-1,3-dimethoxybenzene was used in the regioselective synthesis of TMC-264, tricyclic structure having chloro-1H-dibenzo[b,d]pyran-4,6-dione skeleton1. |
| Melting point | 34-36 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-1,3-dimethoxybenzene used for?
+
5-Chloro-1,3-dimethoxybenzene is primarily used as a building block in organic synthesis and in pharmaceutical research. It was specifically used in the synthesis of TMC-264.
What is the CAS number and chemical formula for 5-Chloro-1,3-dimethoxybenzene?
+
The CAS number is 7051-16-3 and the linear formula is ClC<sub>6</sub>H<sub>3</sub>(OCH<sub>3</sub>)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 5-Chloro-1,3-dimethoxybenzene with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 5-Chloro-1,3-dimethoxybenzene be handled safely?
+
Handle 5-Chloro-1,3-dimethoxybenzene with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator if needed, as it can cause skin irritation, serious eye irritation, and respiratory irritation (H315, H319, H335).
Is 5-Chloro-1,3-dimethoxybenzene available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Chloro-1,3-dimethoxybenzene.
How can I request a quote or sample?
+
To request a quote or sample of 5-Chloro-1,3-dimethoxybenzene, please contact our sales department through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis