5-Carboxythiophene-2-boronic acid pinacol ester

CAS 779335-05-6C11H15BO4SChemical Synthesis

5-Carboxythiophene-2-boronic acid pinacol ester (CAS: 779335-05-6) is a heteroaryl boronate ester with the molecular formula C11H15BO4S and a molecular weight of 254.11 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. It is widely utilised in the development of novel organic molecules within the pharmaceutical and materials science sectors.

IUPAC: 5-Carboxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene,5-Carboxy-2-thienylboronic acid pinacol ester
Synonyms: 5-Carboxy-2-thienylboronic acid pinacol ester5-Carboxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene

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5-Carboxythiophene-2-boronic acid pinacol ester (C11H15BO4S) — chemical structure, CAS 779335-05-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents

01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

This boronate ester is an effective coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. It facilitates the synthesis of complex biaryl and heteroaryl systems.

Organic Synthesis Intermediate

The compound functions as a versatile intermediate for constructing more complex molecular architectures. Its thiophene core and boronate ester functionality offer multiple points for chemical modification.

Pharmaceutical Research and Development

It is employed in medicinal chemistry for the synthesis of potential drug candidates. The thiophene moiety is a common structural motif in pharmacologically active compounds.

Materials Science

The unique electronic properties of the thiophene ring make this compound useful in the development of organic electronic materials, such as conductive polymers or organic light-emitting diodes (OLEDs).

02 /Properties

Molecular weight	254.11
Empirical formula	C11H15BO4S
Assay	96%
Melting point	176-181 °C

03 /Identifiers & registry

CAS number

779335-05-6

MDL number

MFCD09952060

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 5-Carboxythiophene-2-boronic acid pinacol ester used for?

This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, in the development of pharmaceuticals, and in materials science.

What is the CAS number and formula for 5-Carboxythiophene-2-boronic acid pinacol ester?

The CAS number is 779335-05-6, and the molecular formula is C11H15BO4S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical at a purity of 96%. We do not represent it as USP/BP/EP or any other pharmacopoeia grade.

What are the safety and handling considerations for this product?

This compound is classified as hazardous. It is harmful if swallowed, causes skin irritation, and causes serious eye irritation. Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, should be used. Handle in a well-ventilated area.

How is 5-Carboxythiophene-2-boronic acid pinacol ester packed and shipped?

Products are packed securely in compliance with international shipping regulations. TSS is an experienced global exporter of chemicals.

How can I request a quote or sample?

To request a quote or sample, please use the contact form on our website or contact our sales team directly. Please reference the product name and CAS number.