1-Bromo-2,4,5-trifluorobenzene
1-Bromo-2,4,5-trifluorobenzene (CAS: 327-52-6) is a halogenated aromatic compound with the molecular formula BrC6H2F3 and a molecular weight of 210.98 g/mol. This fluorinated building block serves as a key intermediate in organic synthesis. It is primarily utilised in the preparation of various substituted trifluorobenzoic acids and related compounds, demonstrating its utility in the development of novel molecules for research and advanced chemical applications.
- Synonyms
- 327-52-6BrC6H2F3
Synthesis of Substituted Trifluorobenzoic Acids
1-Bromo-2,4,5-trifluorobenzene is employed in the synthesis of 3-ethenyl, 3-ethynyl, 3-aryl, and 3-cyclopropyl-2,4,5-trifluorobenzoic acids, expanding the scope of trifluorinated aromatic compounds.
Preparation of Brominated Trifluorobenzoic Acids
This compound serves as a precursor for synthesizing 3-bromo-2,5,6-trifluorobenzoic acid, a valuable intermediate in further chemical transformations.
Intermediate for Organic Synthesis
As a versatile aryl fluorinated building block, it facilitates the introduction of the 2,4,5-trifluorophenyl moiety into complex molecular structures.
| Molecular weight | 210.98 |
|---|---|
| Linear formula | BrC6H2F3 |
| Assay | 99% |
| Boiling point | 144 °C(lit.) |
| Density | 1.802 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.485(lit.) |
| Solubility | water: insoluble |
| Melting point | −19 °C(lit.) |
| Application | 1-Bromo-2,4,5-trifluorobenzene has been used in the synthesis of:• 3-ethenyl, 3-ethynyl, 3-aryl and 3-cyclopropyl-2,4,5-trifluorobenzoic acids1• 3-bromo-2,5,6-trifluorobenzoic acid and 2,4,5-trifluorobenzoic acid2 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 56 °C / 132.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-2,4,5-trifluorobenzene used for?
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It is primarily used as a building block in organic synthesis for the preparation of various substituted trifluorobenzoic acids and other fluorinated aromatic compounds.
What is the CAS number and chemical formula for 1-Bromo-2,4,5-trifluorobenzene?
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The CAS number is 327-52-6 and the linear chemical formula is BrC6H2F3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-2,4,5-trifluorobenzene with a minimum purity of 99%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Bromo-2,4,5-trifluorobenzene be handled safely?
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1-Bromo-2,4,5-trifluorobenzene is a flammable liquid and vapour (H226), and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area, away from ignition sources.
Does Tech Serve Solutions export 1-Bromo-2,4,5-trifluorobenzene?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Bromo-2,4,5-trifluorobenzene.
How can I request a quote or sample?
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To request a quote or a sample of 1-Bromo-2,4,5-trifluorobenzene, please contact our sales team through the website or by phone.
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