5-Bromo-3-pyridineboronic acid pinacol ester
5-Bromo-3-pyridineboronic acid pinacol ester (CAS: 452972-13-3) is a valuable organoboron compound with the empirical formula C11H15BBrNO2 and a molecular weight of 283.96 g/mol. This pyridine derivative is primarily utilised as a building block in organic synthesis, particularly in cross-coupling reactions. Its structure makes it an important intermediate for the development of complex molecules in pharmaceutical and materials science research.
- IUPAC
- 5-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Synonyms
- 5-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Suzuki-Miyaura Coupling Reagent
Serves as a key coupling partner in Suzuki-Miyaura reactions for the formation of carbon-carbon bonds. It is instrumental in introducing the 5-bromo-3-pyridyl moiety into diverse organic frameworks.
Pharmaceutical Intermediate
A versatile intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programmes. Facilitates the construction of novel heterocyclic compounds with potential therapeutic activity.
Materials Science Research
Utilised in the development of functional materials, such as organic light-emitting diodes (OLEDs) and polymers, where precise structural control is required.
Agrochemical Synthesis
Applicable in the synthesis of novel agrochemical compounds, contributing to the development of advanced crop protection agents.
| Molecular weight | 283.96 |
|---|---|
| Empirical formula | C11H15BBrNO2 |
| Assay | 90% |
| Melting point | 71-75 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-3-pyridineboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura coupling reactions, for the creation of new carbon-carbon bonds. It serves as an important intermediate in the development of pharmaceuticals, agrochemicals, and functional materials.
What are the CAS number and formula for 5-Bromo-3-pyridineboronic acid pinacol ester?
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The CAS number is 452972-13-3 and the empirical formula is C11H15BBrNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 90%. It is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 5-Bromo-3-pyridineboronic acid pinacol ester be handled?
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Due to its potential to cause skin and eye irritation (H315, H319), handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Refer to the Safety Data Sheet for full details.
How is 5-Bromo-3-pyridineboronic acid pinacol ester packed and exported?
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Products are carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions.
How can I request a sample or quote?
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To request a sample or a quote, please visit the Tech Serve Solutions website or contact our sales team directly with your specific requirements.
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