5-Bromo-2-methoxyphenylboronic acid
5-Bromo-2-methoxyphenylboronic acid (CAS: 89694-45-1) is an organoboron compound with the formula BrC6H3(OCH3)B(OH)2 and a molecular weight of 230.85 g/mol. This disubstituted aryl boronic acid serves as a valuable building block in organic synthesis. It is primarily employed as a reactant in Suzuki-Miyaura cross-coupling reactions and in the synthesis of complex molecules, such as luminescent tweezers-like aromatic compounds.
- IUPAC
- 3-Bromo-6-methoxyphenylboronic acid,5-Bromo-2-methoxybenzeneboronic acid
- Synonyms
- 3-Bromo-6-methoxyphenylboronic acid5-Bromo-2-methoxybenzeneboronic acid
Suzuki-Miyaura Cross-Coupling Reactions
5-Bromo-2-methoxyphenylboronic acid is a key reactant in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds. This enables the synthesis of biaryl compounds and other complex organic structures.
Synthesis of Luminescent Molecules
This compound is utilised in the construction of tweezers-like aromatic molecules exhibiting luminescent properties. Such molecules have potential applications in materials science and sensing.
Organic Synthesis Intermediate
As a versatile aryl boronic acid derivative, it functions as an important intermediate in various multi-step organic syntheses, allowing for the introduction of the 5-bromo-2-methoxyphenyl moiety.
| Molecular weight | 230.85 |
|---|---|
| Linear formula | BrC6H3(OCH3)B(OH)2 |
| Application | Reactant for:• Tweezers-like aromatic molecules with luminescent properties1• Suzuki-Miyaura cross-coupling reactions2,3 |
| Melting point | 130-135 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-methoxyphenylboronic acid used for?
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5-Bromo-2-methoxyphenylboronic acid is used as a reactant in Suzuki-Miyaura cross-coupling reactions and in the synthesis of luminescent aromatic molecules. It is a valuable intermediate in organic synthesis.
What is the CAS number and chemical formula for 5-Bromo-2-methoxyphenylboronic acid?
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The CAS number is 89694-45-1, and the chemical formula is BrC6H3(OCH3)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Bromo-2-methoxyphenylboronic acid as a research or technical grade material. TSS does not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should 5-Bromo-2-methoxyphenylboronic acid be handled safely?
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This compound is a warning-level irritant, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is 5-Bromo-2-methoxyphenylboronic acid packed, shipped, and exported?
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5-Bromo-2-methoxyphenylboronic acid is carefully packed to ensure stability during transit. Tech Serve Solutions is experienced in global export of fine chemicals and laboratory reagents, adhering to all relevant shipping regulations.
How can I request a quote or sample for 5-Bromo-2-methoxyphenylboronic acid?
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To request a quote or a sample of 5-Bromo-2-methoxyphenylboronic acid, please contact our sales team through the website or by phone. We are happy to assist with your chemical sourcing needs.
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