5-Bromo-2-methoxybenzylzinc chloride solution
5-Bromo-2-methoxybenzylzinc chloride solution (CAS 352530-35-9), with a molecular weight of 300.90 g/mol and formula CH3OC6H3(Br)CH2ZnCl, is an organozinc halide reagent. Supplied as a 0.5 M solution in THF, it is a key intermediate in organic synthesis. Its reactivity makes it valuable for introducing the 5-bromo-2-methoxybenzyl group in various chemical transformations, particularly in the development of complex organic molecules and pharmaceutical intermediates.
Organozinc Reagent in Cross-Coupling Reactions
This compound serves as an organozinc halide nucleophile in transition-metal-catalyzed cross-coupling reactions. It is employed to form new carbon-carbon bonds by coupling with various electrophiles.
Synthesis of Pharmaceutical Intermediates
Its specific structure allows for the targeted introduction of the 5-bromo-2-methoxybenzyl moiety, which can be a crucial building block in the synthesis of complex pharmaceutical agents.
Advanced Organic Synthesis
As a specialised organometallic reagent, it facilitates advanced synthetic strategies in academic and industrial research laboratories. It is useful for constructing intricate molecular architectures.
| Molecular weight | 300.90 |
|---|---|
| Linear formula | CH3OC6H3(Br)CH2ZnCl |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-methoxybenzylzinc chloride solution used for?
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5-Bromo-2-methoxybenzylzinc chloride solution is used as an organozinc halide reagent in organic synthesis, particularly for forming carbon-carbon bonds in cross-coupling reactions and as a building block for pharmaceutical intermediates.
What are the CAS number and formula for this product?
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The CAS number is 352530-35-9 and the linear formula is CH3OC6H3(Br)CH2ZnCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not claim USP, BP, or EP pharmacopoeia grades unless explicitly stated in the product specifications.
What are the key safety concerns when handling this chemical?
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This is a highly flammable liquid and vapour (H225), causes severe skin burns and eye damage (H314), may cause respiratory irritation (H335), and is suspected of causing cancer (H351). It may form explosive peroxides and reacts violently with water. Strict handling precautions are required.
How is 5-Bromo-2-methoxybenzylzinc chloride solution shipped and exported?
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This product is classified under UN 2056, Hazard Class 3, Packing Group II. It requires specialised packaging and handling for safe transport and international export, adhering to all relevant dangerous goods regulations.
How can I request a sample or a quote for this product?
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Please contact our sales team via the website or direct email to request a sample or a formal quotation for 5-Bromo-2-methoxybenzylzinc chloride solution.
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