5-Bromo-2-hydroxybenzyl alcohol
5-Bromo-2-hydroxybenzyl alcohol (CAS: 2316-64-5; Formula: BrC6H3(OH)CH2OH; MW: 203.03) is a brominated organic compound featuring both alcohol and phenol functionalities. It serves as a versatile building block in organic synthesis. This chemical is utilised in the preparation of complex heterocyclic compounds and functionalised aromatic systems, finding application in research and development settings for novel molecule construction.
- IUPAC
- 5-Bromosalicyl alcohol,Bromosaligenin
Synthesis of Heterocyclic Compounds
5-Bromo-2-hydroxybenzyl alcohol is a key intermediate in the synthesis of various heterocyclic systems. For example, it has been employed in the preparation of fused ring systems such as benzoxazines and phosphorin derivatives, highlighting its utility in complex molecule construction.
Precursor for Pharmaceutical Intermediates
The compound acts as a valuable building block for constructing more elaborate molecular architectures. Its functional groups allow for diverse synthetic transformations, making it a useful precursor in the development pathways of potential pharmaceutical agents or related research chemicals.
Research and Development
Used in laboratory settings for organic synthesis research, 5-Bromo-2-hydroxybenzyl alcohol enables chemists to explore new reaction pathways and develop novel compounds. Its specific structure facilitates the introduction of bromine and hydroxyl functionalities into target molecules.
| Molecular weight | 203.03 |
|---|---|
| Linear formula | BrC6H3(OH)CH2OH |
| Assay | ≥98% |
| Solubility | water: soluble0.7% at 25 °C(lit.)olive oil: soluble4.8%(lit.)alcohol: freely soluble(lit.)benzene: moderately soluble(lit.)chloroform: moderately soluble(lit.)diethyl ether: freely soluble(lit.)ethyl acetate: freely soluble(lit.)hot water: soluble(lit.) |
| Application | 5-Bromo-2-hydroxybenzyl alcohol was used in the synthesis of:• 7-bromo-2,3-diphenyl-5H-imidazo[2,1-b][1,3]benzoxazine1• 6-bromo-2-octyl-4H-1,3,2-benzodioxaphosphorin 2-oxide2• 4-bromo-2-(5-iodo-1H-indol-3-ylmethyl)- phenol3 |
| Melting point | 110-112 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-hydroxybenzyl alcohol used for?
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5-Bromo-2-hydroxybenzyl alcohol is primarily used as a building block in organic synthesis, particularly for the preparation of complex heterocyclic compounds and functionalised aromatic systems in research and development.
What is the CAS number and chemical formula for 5-Bromo-2-hydroxybenzyl alcohol?
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The CAS number is 2316-64-5 and the chemical formula is BrC6H3(OH)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Bromo-2-hydroxybenzyl alcohol with a minimum assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 5-Bromo-2-hydroxybenzyl alcohol be handled?
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Handle 5-Bromo-2-hydroxybenzyl alcohol with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation, as it may cause skin irritation, serious eye irritation, and respiratory irritation (H315-H319-H335).
Is 5-Bromo-2-hydroxybenzyl alcohol a controlled substance?
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Based on the provided data, 5-Bromo-2-hydroxybenzyl alcohol is not indicated as a controlled substance.
How is 5-Bromo-2-hydroxybenzyl alcohol packed and exported?
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Tech Serve Solutions exports fine chemicals globally, adhering to strict packaging and shipping regulations to ensure safe transit and compliance with international trade standards.
How can I request a quote or sample for 5-Bromo-2-hydroxybenzyl alcohol?
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Please contact our sales team through the website or by phone to request a quotation or a sample of 5-Bromo-2-hydroxybenzyl alcohol.
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