5-Bromo-2-fluoro-3-pyridineboronic acid pinacol ester
5-Bromo-2-fluoro-3-pyridineboronic acid pinacol ester (CAS: 1073353-50-0) is a key organoboron compound with the molecular formula C11H14BBrFNO2 and a molecular weight of 301.95 g/mol. Supplied as a technical-grade reagent with an assay of 97%, it serves as a valuable building block in organic synthesis, particularly for introducing functionalised pyridine rings into complex molecules via cross-coupling reactions.
- IUPAC
- 5-Bromo-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Synonyms
- 5-Bromo-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Suzuki-Miyaura Cross-Coupling
Utilised as a coupling partner in Suzuki-Miyaura reactions to form carbon-carbon bonds. This reaction is extensively employed in the synthesis of pharmaceuticals and advanced materials, leveraging the reactivity of the boronate ester moiety.
Heterocyclic Chemistry
Acts as a versatile synthon for constructing functionalised pyridine derivatives. The presence of bromine and fluorine atoms allows for selective functionalisation, enabling access to diverse heterocyclic scaffolds.
Medicinal Chemistry
Incorporated into the synthesis of novel drug candidates and biologically active molecules. The pyridine core is a common feature in many pharmaceuticals, and this reagent provides a controlled method for its elaboration.
| Molecular weight | 301.95 |
|---|---|
| Empirical formula | C11H14BBrFNO2 |
| Assay | 97% |
| Melting point | 46-50 °C |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Bromo-2-fluoro-3-pyridineboronic acid pinacol ester used for?
+
This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for constructing complex molecules containing functionalised pyridine rings.
What is the CAS number and formula for 5-Bromo-2-fluoro-3-pyridineboronic acid pinacol ester?
+
The CAS number is 1073353-50-0 and the empirical formula is C11H14BBrFNO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with a minimum assay of 97%. It is supplied as a technical/research grade reagent and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for this product?
+
This compound has a flash point above 110 °C and a melting point of 46-50 °C. It is classified under WGK Germany 1. Refer to the Safety Data Sheet (SDS) for comprehensive handling, storage, and personal protective equipment guidelines. Avoid contact with skin and eyes, and ensure adequate ventilation.
How is this chemical packed, shipped, and exported?
+
Tech Serve Solutions offers this chemical in various packaging sizes suitable for laboratory and industrial use. We adhere to strict international shipping regulations for chemical exports.
How can I request a sample or a quote?
+
To request a sample or a quote for 5-Bromo-2-fluoro-3-pyridineboronic acid pinacol ester, please visit the product page on our website or contact our sales department directly.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis