5,6-Dimethoxyindole
5,6-Dimethoxyindole (CAS: 14430-23-0) is a heterocyclic compound with the molecular formula C10H11NO2 and a molecular weight of 177.20 g/mol. This indole derivative serves as a valuable building block in organic synthesis. It is primarily utilised as a reactant in the development of various complex organic molecules, including potential pharmaceutical agents and biologically active compounds. Its structural features make it a useful intermediate for constructing fused ring systems and substituted indoles.
- Synonyms
- C10H11NO2
Synthesis of Indolylhydroxyoxindoles
Utilised as a reactant in the enantioselective Friedel-Crafts reaction for synthesising complex indolylhydroxyoxindole structures.
Preparation of Benzyl Trimethoxyindoles
Serves as a key reactant in the synthetic route towards benzyl trimethoxyindole derivatives.
Development of HIV-1 Inhibitors
Employed as a reactant in the synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives, investigated for their potential as HIV-1 inhibitors.
Antitumor Agent Analogs Synthesis
Acts as a reactant in the preparation of 1-aroylindole 3-aroylindole analogs, including combretastatin A-4 analogs, studied for antitumor activity and tubulin polymerization inhibition.
Tryptophanol Derivatives Preparation
Used as a reactant for the preparation of tryptophanol derivatives through the Grignard reaction.
| Molecular weight | 177.20 |
|---|---|
| Empirical formula | C10H11NO2 |
| Assay | 99% |
| Application | • Reactant in synthesis of indolylhydroxyoxindoles via enantioselective Friedel-Crafts reaction• Reactant in synthesis of benzyl trimethoxyindoles• Reactant for synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitors• Reactant for synthesis of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors• Reactant for preparation of tryptophanol derivatives via the Grignard reaction |
| Melting point | 154-157 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5,6-Dimethoxyindole used for?
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5,6-Dimethoxyindole is primarily used as a reactant in organic synthesis. It serves as a building block for creating various complex molecules, including indolylhydroxyoxindoles, benzyl trimethoxyindoles, potential HIV-1 inhibitors, antitumor agent analogs, and tryptophanol derivatives.
What is the CAS number and formula for 5,6-Dimethoxyindole?
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The CAS number for 5,6-Dimethoxyindole is 14430-23-0, and its empirical formula is C10H11NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5,6-Dimethoxyindole with an assay of 99%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and chemical synthesis applications.
How should 5,6-Dimethoxyindole be handled safely?
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According to GHS classifications, handling 5,6-Dimethoxyindole requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is 5,6-Dimethoxyindole shipped and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 5,6-Dimethoxyindole, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for 5,6-Dimethoxyindole?
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Please contact our sales team via the website or by phone to request a sample or a formal quotation for 5,6-Dimethoxyindole.
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