5-(1,3-Dioxolan-2-yl)-2-thienylzinc bromide solution
5-(1,3-Dioxolan-2-yl)-2-thienylzinc bromide solution (CAS 307531-84-6), with a molecular weight of 300.49, is a versatile organozinc reagent. It is supplied as a 0.5 M solution in Tetrahydrofuran (THF). This compound is primarily utilised in organic synthesis for the introduction of the 5-(1,3-dioxolan-2-yl)-2-thienyl moiety into various molecular structures, particularly in the construction of complex organic molecules and pharmaceutical intermediates.
- Synonyms
- C7H7BrO2SZn
Cross-Coupling Reactions
This organozinc bromide acts as a nucleophilic coupling partner in transition metal-catalysed cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides and triflates.
Heterocyclic Synthesis
It is employed in the synthesis of functionalised thiophene derivatives, which are common structural motifs in pharmaceuticals, agrochemicals, and materials science.
Pharmaceutical Intermediate Synthesis
The compound serves as a building block for the preparation of complex molecules with potential biological activity, contributing to the development of new therapeutic agents.
| Molecular weight | 300.49 |
|---|---|
| Empirical formula | C7H7BrO2SZn |
| Boiling point | 65 °C |
| Density | 1.017 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-(1,3-Dioxolan-2-yl)-2-thienylzinc bromide solution used for?
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This organozinc reagent is used in organic synthesis, particularly for cross-coupling reactions and the construction of functionalised thiophene derivatives and pharmaceutical intermediates.
What is the CAS number and formula for this compound?
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The CAS number is 307531-84-6, and its empirical formula is C7H7BrO2SZn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a 0.5 M solution in THF. TSS does not represent this product as USP/BP/EP or any pharmacopoeial grade.
How should 5-(1,3-Dioxolan-2-yl)-2-thienylzinc bromide solution be handled and stored?
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This solution is highly flammable (Flash Point -17 °C) and may form explosive peroxides. Handle with extreme care, avoiding ignition sources and oxidising agents. It should be stored under refrigeration at 2-8°C.
Is this product regulated as a controlled substance?
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The provided data does not indicate that this substance is a controlled substance.
How is this product packed, shipped, and exported?
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This product is shipped as UN 2056, Hazard Class 3, Packing Group II, according to ADR regulations. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or a quote?
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Please contact Tech Serve Solutions directly through our website or by phone to request a sample or a quotation for this product.
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