4-Phenylbutyric acid
4-Phenylbutyric acid (CAS: 1821-12-1) is an organic compound with the molecular formula C<sub>6</sub>H<sub>5</sub>(CH<sub>2</sub>)<sub>3</sub>COOH and a molecular weight of 164.20 g/mol. This carboxylic acid derivative functions as a crucial building block in chemical synthesis. It is recognised for its role in modulating endoplasmic reticulum (ER) stress and acts as a chemical chaperone. Its applications extend to cell biology research, particularly in cell signalling and neuroscience.
Chemical Synthesis
4-Phenylbutyric acid serves as a versatile organic building block. It is utilised in the synthesis of more complex molecules within pharmaceutical and chemical research.
Endoplasmic Reticulum (ER) Stress Modulation
This compound is employed as a chemical activator and inhibitor of ER stress. It functions as a chemical ER chaperone, aiding in protein folding and cellular homeostasis.
Cell Biology Research
It is used in studies related to cell signalling and neuroscience. Its influence on ER stress pathways makes it a valuable tool for investigating cellular responses to various stimuli.
| Molecular weight | 164.20 |
|---|---|
| Linear formula | C6H5(CH2)3COOH |
| Assay | ≥99.0% (HPLC) |
| Boiling point | 165 °C/10 mmHg(lit.) |
| Melting point | 49-51 °C(lit.)49-52 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Phenylbutyric acid primarily used for?
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4-Phenylbutyric acid is primarily used as a building block in chemical synthesis, for modulating endoplasmic reticulum (ER) stress, and in cell biology research, particularly in cell signalling and neuroscience.
What are the CAS number and molecular formula for 4-Phenylbutyric acid?
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The CAS number is 1821-12-1 and the molecular formula is C<sub>6</sub>H<sub>5</sub>(CH<sub>2</sub>)<sub>3</sub>COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Phenylbutyric acid with a minimum assay of ≥99.0% (HPLC). This is a research-grade chemical and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for 4-Phenylbutyric acid?
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4-Phenylbutyric acid is classified with GHS hazards. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. Handle in a well-ventilated area.
Can Tech Serve Solutions export 4-Phenylbutyric acid?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Phenylbutyric acid.
How can I request a sample or a quote for 4-Phenylbutyric acid?
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Please contact our sales team via the website or by phone to request a sample or a quotation for 4-Phenylbutyric acid.
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