4-Phenoxybenzenesulfonyl chloride
4-Phenoxybenzenesulfonyl chloride (CAS: 1623-92-3; Formula: C12H9ClO3S) is a key organic intermediate with a molecular weight of 268.72 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly for the introduction of the phenoxybenzenesulfonyl moiety into various organic structures. It is widely utilised in research and development for creating novel compounds across diverse chemical fields.

Organic Synthesis Reagent
4-Phenoxybenzenesulfonyl chloride is employed as a reactive intermediate for the synthesis of complex organic molecules. Its sulfonyl chloride group readily undergoes reactions with nucleophiles like amines and alcohols.
Building Block for Specialty Chemicals
The compound acts as a versatile building block in the development of specialty chemicals. It facilitates the construction of molecules with specific electronic and structural properties for advanced applications.
Pharmaceutical Intermediate Research
It is utilised in the research and development of potential pharmaceutical agents, where the phenoxybenzenesulfonyl group can impart specific biological activities or modify pharmacokinetic profiles.
| Molecular weight | 268.72 |
|---|---|
| Empirical formula | C12H9ClO3S |
| Assay | 97% |
| Melting point | 41-44 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Phenoxybenzenesulfonyl chloride used for?
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4-Phenoxybenzenesulfonyl chloride is primarily used as a building block and intermediate in organic synthesis and chemical research for creating new compounds, including potential pharmaceutical agents.
What is the CAS number and formula for 4-Phenoxybenzenesulfonyl chloride?
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The CAS number is 1623-92-3 and the empirical formula is C12H9ClO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Phenoxybenzenesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Phenoxybenzenesulfonyl chloride be handled?
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Handling requires extreme caution due to its corrosive nature (H314). Use with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a suitable respirator. Ensure adequate ventilation. Refer to the safety data sheet for full guidance.
How is 4-Phenoxybenzenesulfonyl chloride packed and shipped?
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This chemical is shipped as UN 3261, Class 8, Packing Group III, indicating it is a corrosive solid. It is exported globally by Tech Serve Solutions, adhering to all relevant transport regulations.
How can I request a quote or sample for 4-Phenoxybenzenesulfonyl chloride?
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To request a quote or sample, please use the contact form on our website or contact our sales team directly with your requirements.
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