4-Nitrophenylhydrazine
4-Nitrophenylhydrazine (CAS: 100-16-3), with the molecular formula O2NC6H4NHNH2 and a molecular weight of 153.14 g/mol, is a chemical compound supplied by Tech Serve Solutions. This substance, containing at least 30% water as a stabilizer, serves primarily as a reagent in analytical chemistry and organic synthesis. Its utility extends to derivatization processes, particularly in chromatographic applications.

Analytical Reagent
4-Nitrophenylhydrazine is employed as a reagent in analytical chemistry for the detection and quantification of various substances. Its reactions can yield derivatives suitable for spectroscopic or chromatographic analysis.
Derivatization Agent
It is used as a derivatization agent, especially in High-Performance Liquid Chromatography (HPLC), to convert analytes into detectable derivatives. This is crucial for improving separation and detection limits.
Organic Synthesis Building Block
The compound serves as a building block in organic synthesis. It can be used to introduce the 4-nitrophenylhydrazino moiety into more complex molecules through various chemical reactions.
| Molecular weight | 153.14 |
|---|---|
| Linear formula | O2NC6H4NHNH2 |
| Assay | 96% |
| Contains / stabiliser | ≥30% water as stabilizer |
| Melting point | 156 °C (dec.)(lit.) |


Hazard statements
- H228Flammable solid
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3376 4.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 5-11-21/22 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitrophenylhydrazine used for?
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4-Nitrophenylhydrazine is primarily used as an analytical reagent, a derivatization agent, particularly in HPLC, and as a building block in organic synthesis.
What is the CAS number and formula for 4-Nitrophenylhydrazine?
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The CAS number for 4-Nitrophenylhydrazine is 100-16-3, and its linear formula is O2NC6H4NHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitrophenylhydrazine with an assay of 96%. This is typically supplied as a technical or research grade; TSS does not represent this product as USP, BP, or EP grade.
What are the main safety concerns with 4-Nitrophenylhydrazine?
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4-Nitrophenylhydrazine is a flammable solid (H228) and is harmful if swallowed (H302), in contact with skin (H312), and can cause skin irritation (H315), allergic skin reaction (H317), and respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator.
How is 4-Nitrophenylhydrazine packed, shipped, and exported?
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4-Nitrophenylhydrazine is packed according to relevant safety and transport regulations for chemical substances. Tech Serve Solutions exports this compound globally, adhering to all international shipping and customs requirements.
How can I request a sample or quote for 4-Nitrophenylhydrazine?
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To request a sample or a quote for 4-Nitrophenylhydrazine, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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