1-Bromo-2,4-dinitrobenzene
1-Bromo-2,4-dinitrobenzene (CAS 584-48-5), with the linear formula BrC6H3(NO2)2 and a molecular weight of 247.00 g/mol, is an organic compound typically supplied at 97% purity. It functions as a key building block in chemical synthesis. Historically, it has been employed in the preparation of 2,4-dinitrophenol and as a substrate in specific biochemical assays, such as those involving prostaglandin D2 synthase.
- Synonyms
- BrC6H3(NO2)2
Preparation of 2,4-Dinitrophenol
1-Bromo-2,4-dinitrobenzene has been utilised in the synthesis of 2,4-dinitrophenol through reactions involving KO2-crown ether complexes in benzene.
Biochemical Assays
This compound serves as a substrate in protein determination and in glutathione S-transferase (GST) assays, particularly for studying chicken and rat prostaglandin D2 synthase (PGDS).
Organic Synthesis Intermediate
As a dinitrophenylating agent and a functionalised aromatic bromide, it is a versatile intermediate for introducing the 2,4-dinitrophenyl moiety in various organic synthesis pathways.
| Molecular weight | 247.00 |
|---|---|
| Linear formula | BrC6H3(NO2)2 |
| Assay | 97% |
| Application | 1-Bromo-2,4-dinitrobenzene has been used:• in the preparation of 2,4-dinitrophenol via treatment with KO2-crown ether complex in benzene1• as substrate in protein determination and glutathione S-transferase (GST) assay of chicken and rat prostaglandin D2 synthase (PGDS)2 |
| Melting point | 71-73 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-2,4-dinitrobenzene used for?
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1-Bromo-2,4-dinitrobenzene is primarily used as a building block in chemical synthesis. It has applications in preparing other compounds, such as 2,4-dinitrophenol, and as a substrate in biochemical assays like protein determination and glutathione S-transferase (GST) assays.
What are the CAS number and formula for 1-Bromo-2,4-dinitrobenzene?
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The CAS number for 1-Bromo-2,4-dinitrobenzene is 584-48-5, and its linear formula is BrC6H3(NO2)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies 1-Bromo-2,4-dinitrobenzene with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated otherwise in the product documentation.
How should 1-Bromo-2,4-dinitrobenzene be handled safely?
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1-Bromo-2,4-dinitrobenzene is classified with hazards H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, should be used during handling. Refer to the Safety Data Sheet for comprehensive safety information.
Is 1-Bromo-2,4-dinitrobenzene a controlled substance?
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Based on the provided data, 1-Bromo-2,4-dinitrobenzene is not listed as a controlled substance.
How is 1-Bromo-2,4-dinitrobenzene packed and exported?
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1-Bromo-2,4-dinitrobenzene is shipped and exported according to relevant regulations, including UN 3077 classification. Specific packaging details are available upon request.
How can I request a sample or quote?
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To request a sample or a quote for 1-Bromo-2,4-dinitrobenzene, please contact the Tech Serve Solutions sales department through our website or by phone.
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