1-Bromo-2,5-dimethoxybenzene

CAS 25245-34-5BrC6H3(OCH3)2Chemical Synthesis

1-Bromo-2,5-dimethoxybenzene (CAS: 25245-34-5) is an organic compound with the linear formula BrC 6H3(OCH3)2 and a molecular weight of 217.06 g/mol. This aromatic ether serves as a valuable building block in organic synthesis. It is primarily utilised in the preparation of more complex molecules, including specialised chemical intermediates and research compounds. TSS supplies this chemical with a purity of 98%.

Synonyms: BrC6H3(OCH3)2

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1-Bromo-2,5-dimethoxybenzene (BrC6H3(OCH3)2) — chemical structure, CAS 25245-34-5; Chemistry, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Synthesis of Amino Ketones

1-Bromo-2,5-dimethoxybenzene is employed in the synthesis of specific amino ketone derivatives, such as (S)-(-)-2-[N-(trifluoroacetyl)amino]-1-(2,5-dimethoxy-4-bromophenyl)-1-propanone.

Preparation of Butadiynes

This compound has been utilised in the preparation of complex butadiyne structures. Examples include 1,4-bis{4-[2-(4-pyridyl)ethenyl]phenyl}butadiyne and related dimethoxy derivatives.

Intermediate for Halogenated Aromatics

It serves as a precursor for the synthesis of other halogenated aromatic compounds. For instance, it can be used to prepare 1-bromo-4-iodo-2,5-dimethoxybenzene.

02 /Properties

Molecular weight	217.06
Linear formula	BrC6H3(OCH3)2
Assay	98%
Boiling point	130-131 °C/10 mmHg(lit.)
Density	1.445 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.57(lit.)
Application	1-Bromo-2,5-dimethoxybenzene has been used in preparation of:• S-(-)-2-[N-(trifluoroacetyl)amino]-1-(2,5-dimethoxy-4- bromophenyl)-1-propanone1• 1,4-bis{4-[2-(4-pyridyl)ethenyl]phenyl}butadiyne and 1,4-bis{2,5-dimethoxy-4-[2-(4-pyridyl)ethenyl]phenyl}butadiyne2• 1-bromo-4-iodo-2,5-dimethoxybenzene3

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	113 °C / 235.4 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

25245-34-5

MDL number

MFCD00008355

PubChem substance

24855234

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-Bromo-2,5-dimethoxybenzene used for?

1-Bromo-2,5-dimethoxybenzene is used as a building block in organic synthesis, particularly for preparing amino ketones, butadiynes, and other halogenated aromatic compounds.

What are the CAS number and formula for 1-Bromo-2,5-dimethoxybenzene?

The CAS number is 25245-34-5, and its linear formula is BrC 6H3(OCH3)2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1-Bromo-2,5-dimethoxybenzene with a minimum assay of 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should 1-Bromo-2,5-dimethoxybenzene be handled safely?

1-Bromo-2,5-dimethoxybenzene is a warning chemical that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation, wear appropriate personal protective equipment including eyeshields and gloves, and use a suitable respirator if needed. Refer to the Safety Data Sheet for detailed handling procedures.

How is 1-Bromo-2,5-dimethoxybenzene packed, shipped, and exported?

1-Bromo-2,5-dimethoxybenzene is carefully packed according to international shipping regulations. TSS offers global export services for this chemical.

How can I request a sample or quote for 1-Bromo-2,5-dimethoxybenzene?

To request a sample or a quotation for 1-Bromo-2,5-dimethoxybenzene, please contact the Tech Serve Solutions sales team through our website or by phone.