4-Methyl-1-naphthaleneboronic acid
4-Methyl-1-naphthaleneboronic acid (CAS: 103986-53-4, Formula: CH3C10H6B(OH)2, MW: 186.01) is a crucial aryl boronic acid derivative. It serves as a versatile building block in organic synthesis, particularly as a reactant in Suzuki-Miyaura coupling reactions. This compound is indispensable for constructing complex molecular architectures in academic research and industrial chemical development. Tech Serve Solutions reliably supplies this intermediate with a guaranteed assay of ≥95%.
- IUPAC
- (4-Methylnaphth-1-yl)boronic acid,4-Methyl-1-naphthalenylboronic acid
- Synonyms
- 4-Methyl-1-naphthalenylboronic acid(4-Methylnaphth-1-yl)boronic acid
Suzuki-Miyaura Coupling
This compound is a key reactant in the Suzuki-Miyaura cross-coupling reaction, a Nobel Prize-winning methodology for carbon-carbon bond formation. It facilitates the synthesis of biaryl compounds and other complex organic structures.
Organic Synthesis Intermediate
As a substituted aryl boronic acid, it serves as a valuable intermediate in the synthesis of diverse organic molecules. Its structure allows for targeted functionalisation in multi-step synthetic routes.
Research and Development
Used extensively in academic and industrial research laboratories for the development of new pharmaceuticals, agrochemicals, and advanced materials. Its participation in cross-coupling reactions makes it a staple in modern synthetic chemistry.
| Molecular weight | 186.01 |
|---|---|
| Linear formula | CH3C10H6B(OH)2 |
| Assay | ≥95% |
| Application | Reactant for:Suzuki-Miyaura coupling1,2 |
| Melting point | 229-235 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methyl-1-naphthaleneboronic acid used for?
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4-Methyl-1-naphthaleneboronic acid is primarily used as a reactant in Suzuki-Miyaura coupling reactions for the synthesis of complex organic molecules. It is also a valuable intermediate in general organic synthesis and research and development.
What are the CAS number and chemical formula?
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The CAS number for 4-Methyl-1-naphthaleneboronic acid is 103986-53-4, and its chemical formula is CH3C10H6B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methyl-1-naphthaleneboronic acid with a purity of ≥95%. This is a technical/research grade material, and TSS does not represent it as USP/BP/EP.
How should 4-Methyl-1-naphthaleneboronic acid be handled safely?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
Is this chemical suitable for international export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Methyl-1-naphthaleneboronic acid, and can facilitate international shipments.
How can I request a quote or sample?
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To request a quote or sample of 4-Methyl-1-naphthaleneboronic acid, please contact our sales department through the TSS website or via direct inquiry.
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