4-Methyl-1-naphthylmagnesium bromide
4-Methyl-1-naphthylmagnesium bromide (CAS 115913-58-1) is an organometallic compound with the linear formula C10H6CH3MgBr and a molecular weight of 245.40. Supplied as a solution in Tetrahydrofuran (THF) at a concentration of 0.25 M, this Grignard reagent serves as a versatile building block in organic synthesis. Its reactivity allows for the introduction of the 4-methyl-1-naphthyl group into various organic molecules, facilitating the construction of complex chemical structures.
Organic Synthesis
This Grignard reagent is widely employed as a nucleophilic source of the 4-methyl-1-naphthyl moiety in carbon-carbon bond-forming reactions. It can react with electrophiles such as aldehydes, ketones, esters, and epoxides to construct more elaborate molecular frameworks.
Pharmaceutical Intermediate Synthesis
The compound is valuable in the multi-step synthesis of potential pharmaceutical agents, where the incorporation of aryl or naphthyl structures is often a key step in drug discovery and development.
Materials Science Research
It can be utilized in the preparation of novel organic materials or functionalised polymers where the naphthyl group may impart specific electronic or structural properties.
| Molecular weight | 245.40 |
|---|---|
| Linear formula | C10H6CH3MgBr |
| Boiling point | 65 °C(lit.) |
| Density | 0.923 g/mL at 25 °C(lit.) |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methyl-1-naphthylmagnesium bromide used for?
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4-Methyl-1-naphthylmagnesium bromide is primarily used as a Grignard reagent in organic synthesis for introducing the 4-methyl-1-naphthyl group into target molecules. It finds applications in the preparation of pharmaceutical intermediates and novel organic materials.
What is the CAS number and chemical formula for 4-Methyl-1-naphthylmagnesium bromide?
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The CAS number is 115913-58-1, and the linear formula is C10H6CH3MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methyl-1-naphthylmagnesium bromide at a concentration of 0.25 M in THF. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 4-Methyl-1-naphthylmagnesium bromide be handled safely?
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This compound is highly reactive and flammable (Flash Point: -17 °C) and reacts violently with water, potentially forming explosive peroxides. It is corrosive and may cause respiratory irritation. Handle with extreme care in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Use appropriate personal protective equipment, including flame-retardant gloves and eye protection. Store at 2-8°C, away from moisture and ignition sources.
Is this chemical regulated or scheduled?
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Based on the provided data, there is no explicit mention of this chemical being regulated or scheduled under specific controlled substance lists. However, its hazardous nature (Danger, H225-H314-H335-H351) requires careful adherence to safety protocols.
How is 4-Methyl-1-naphthylmagnesium bromide packed, shipped, and exported?
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This product is shipped as a hazardous material under UN 2924, Hazard Class 8(3), Packing Group II. Tech Serve Solutions, as an experienced global supplier, ensures compliant packing and export procedures for reactive chemicals.
How can I request a sample or quote for 4-Methyl-1-naphthylmagnesium bromide?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through the website or by phone, providing your specific requirements and shipping details.
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